Active research studies

Details of all our active research studies which are looking for volunteers, with more information about what each project entails and what kind of volunteers would be most suitable.

Early COPD cohort study

COPD is a life-long condition that makes breathing difficult because the airways have been narrowed. People living with COPD will feel out of breath doing everyday tasks such as housework or walking the dog. Though 20% of people with COPD have never smoked and not all smokers develop COPD - it is mainly caused by smoking from early adulthood. Find out more

The MISTER trial

The MISTER trial is looking at testing whether minimal equipment pulmonary rehabilitation classes are as effective as those that use specialist equipment in terms of the effect on fitness levels, breathlessness and quality of life in the short and medium term. Find out more


See details of the Trust’s performance for all clinical trials reported to the NIHR, for the set-up and delivery of studies in the period from 1 October 2018 to 30 Sept 2019.


Active research studies

Treatment in adults with severe bilateral nasal polyps

Study
A randomised, double-blind, parallel group PhIII study to assess the clinical efficacy and safety of 100 mg SC Mepolizumab as an add on to maintenance treatment in adults with severe bilateral nasal polyps.

IRAS no
220783

Study contact information
Name: 
Aarif Eifan
Email: A.Eifan@rbht.nhs.uk

Principal investigator
Dr Guy Scadding

Click here for more information


Pollen food allergy syndrome in adults with IBS

Study
A prospective observational cohort study to determine the prevalence of pollen food allergy syndrome (PFS) in adults with Irritable Bowel Syndrome (IBS)

IRAS no
229644

Study contact information
Name: 
Dr Isabel Skypala
Email: i.skypala@rbht.nhs.uk

Principal investigator
Dr Isabela Skypala

Click here for more information


Nasal allergen challenge: standardisation as a surrogate for hay fever

Study
Nasal Allergen Challenge: standardisation as a surrogate for hay fever

IRAS no
266165

Study contact information
Name: 
Aarif Eifan
Email: A.Eifan@rbht.nhs.uk

Principal investigator
Professor Stephen Durham

Click here for more information

Cardiac Resynchronisation Therapy in non-responders and previously untreatable patients

Study
Stimulation of the left ventricular endocardium for Cardiac Resynchronisation Therapy in non-responders and previously untreatable patients

IRAS no
288696

Study contact information
Name:
 Paula Rogers
Email: P.Rogers@rbht.nhs.uk

Principal investigator
Dr Mark Mason


Role of ganglionated plexus ablation for catheter ablation of paroxysmal and persistent atrial fibrillation

Study
A pilot study on the role of ganglionated plexus ablation for catheter ablation of paroxysmal and persistent atrial fibrillation

IRAS no
133593

Study contact information
Name:
 Dr Sabine Ernst
Email: s.ernst@rbht.nhs.uk

Principal investigator
Dr Sabine Ernst

Click here for more information


WATCHMAN device in patients unsuitable for oral anticoagulation

Study
Assessment of the WATCHMAN device in patients unsuitable for oral anticoagulation

IRAS no
222284

Study contact information
Name:
 Carmen Chan
Email: L.Chan2@rbht.nhs.uk

Principal investigator
Dr Tom Wong


EndoCRT study

Study
A randomised double-blinded cross over study to evaluate the improvement of left ventricular systolic failure using targeted left ventricular endocardial lead placement in cardiac resynchronisation therapy (EndoCRT)

IRAS no
138184

Study contact information
Name:
 Lisa Jones
Email: l.jones2@rbht.nhs.uk

Principal investigator
Dr Tom Wong

Click here for more information


Immediate coronary angiography after out of hospital cardiac arrest (ARREST)

Study
ImmediAte CoRonary AngiogRaphy aftEr Ventricular Fibrillation OutOfHospital Cardiac ArreST (ARREST)

IRAS no
125842

Study contact information
Name:
 Dr Miles Dalby
Email: M.Dalby@rbht.nhs.uk

Principal investigator
Dr Miles Dalby

Click here for more information


NOAH - AFNET 6

Study
Non-vitamin K antagonist Oral anticoagulants in patients with Atrial High rate episodes

IRAS no
194491

Study contact information
Name:
 Dr Shouvik Haldar
Email: S.Haldar@rbht.nhs.uk

Principal investigator
Dr Shouvik Haldar

Click here for more information


VIVOTM mapping protocol

Study
VIVOTM non-invasive mapping of ventricular arrhythmia

IRAS no
257755

Study contact information
Name:
 Dr Ilaria Cazzoli
Email: I.Cazzoli@rbht.nhs.uk

Principal investigator
Dr Ilaria Cazzoli


SPOT - FRAILTY

Study
A Pilot Study to exPlOre the exisTence and impact of FRAILTY in patients over the age of 70 undergoing cardiac interventions.

IRAS no
264744

Study contact information
Name:
 Paula Rogers
Email: p.rogers@rbht.nhs.uk

Principal investigator
Paula Rogers

Heterogeneity of asthma

Study
Heterogeneity of asthma: a pilot study to investigate its microbiome and how it relates to asthma severity

IRAS no
163724

Study contact information
Name:
 Cai Sim
Email: c.sim@rbht.nhs.uk

Principal investigator
Professor Kian Fan Chung

Click here for more information


Adherence to inhaled corticosteroids in young people with problematic severe asthma

Study
Adherence to inhaled corticosteroids in young people with problematic severe asthma

IRAS no
188453

Study contact information
Name:
 Dr Louise Fleming 
Email: l.fleming@rbht.nhs.uk

Principal investigator
Dr Louise Fleming

Click here for more information


Unwanted effects of inhaled corticosteriods in children with airway diseases

Study
Unwanted effects of inhaled corticosteroids in children with airway diseases

IRAS no
227592

Study contact information
Name:
 Louise Selby 
Email: L.Selby@rbht.nhs.uk

Principal investigator
Dr Louise Fleming

Click here for more information


Fluctuation of airway function in children with asthma phenotype as a predictor of outcome

Study
Fluctuation of airway function in children with asthma phenotype as a predictor of outcome

IRAS no
154768

Study contact information
Name:
 Dr Louise Fleming 
Email: l.fleming@rbht.nhs.uk

Principal investigator
Dr Louise Fleming

Click here for more information


A randomised pragmatic trial of corticosteriod optimisation in severe asthma

Study
A randomised pragmatic trial of corticosteroid optimisation in severe asthma using a composite biomarker algorithm to adjust corticosteroid dose versus standard care 

IRAS no
182421

Study contact information
Name:
 Maria Martins
Email: M.Martins@rbht.nhs.uk

Principal investigator
Dr Andrew Menzies-Gow

Click here for more information


Bronchoscopic evaluation of the Eosinophilic Airway Microbiome (BEAM)

Study
Bronchoscopic evaluation of the Eosinophilic Airway Microbiome (BEAM)

IRAS no
215130

Study contact information
Name:
 Claire McBrien
Email: C.McBrien@rbht.nhs.uk

Principal investigator
Dr Andrew Menzies-Gow

Click here for more information


Severe wheeze and asthma validation study

Study
Pulmonary epithelial barrier and immunological functions at birth and in early life: key determinants of the development of asthma? Severe wheeze and asthma validation study

IRAS no
216021

Study contact information
Name:
 Mindy Gore
Email: s.saglani@imperial.ac.uk

Principal investigator
Professor Sejal Saglani

Click here for more information


Do patterns of airway infection and inflammation distinguish pathophys and asthma? 

Study
Do patterns of airway infection and inflammation distinguish pathophysiological phenotypes in children with wheeze and asthma?

IRAS no
187435

Study contact information
Name:
 Yvonne Bingham
Email: Y.Bingham@rbht.nhs.uk

Principal investigator
Professor Sejal Saglani

Click here for more information


Targets of bronchial thermoplasty in severe asthma

Study
Targets of bronchial thermoplasty in severe asthma

IRAS no
150245

Study contact information
Name:
 Dr Karthikan Srikanthan
Email: K.Srikanthan@rbht.nhs.uk

Principal investigator
Professor Pallav Shah

Click here for more information


Th2-low endotype biomarkers in exercise-induced asthma

Study
Th2-low endotype biomarkers in exercise-induced asthma

IRAS no
203756

Study contact information
Name:
 Sally Meah
Email: sally.meah@imperial.ac.uk

Principal investigator
Dr Omar Usmani

Click here for more information


The use of home-monitoring and mHealth systems to predict asthma control and asthma

Study
The use of home-monitoring and mHealth systems to predict asthma control and asthma exacerbations

IRAS no
185603

Study contact information
Name:
 Paolo Paredi
Email: P.Paredi@rbht.nhs.uk

Principal investigator
Dr Omar Usmani

Click here for more information


National Validation and Sensitivity to Change of the SAQ

Study
National Validation and Sensitivity to Change of a scale to measure quality of life in patients with severe asthma.

IRAS no
250167

Study contact information
Name:
 Rachel Stead
Email: R.Stead@rbht.nhs.uk

Principal investigator
Dr Andrew Menzies-Gow 

Click here for more information


Phase IIA study of PC945 in Aspergillosis on Asthmatic subjects

Study
A double-blind, placebo-controlled study to assess the effects of inhaled PC945 in the treatment of culture-positive Aspergillus fumigatus infection in subjects with moderate to severe asthma

IRAS no
246673

Study contact information
Name:
 Najwa Soussi
Email: n.soussi@rbht.nhs.uk

Principal investigator
Dr Darius Armstrong-James

Click here for more information

Utilising novel dipole density capabilities to objectively visualise the etiology of recurrent atrial fibrillation following a failed AF ablation

Study
Utilising novel dipole density capabilities to objectively visualize the etiology of recurrent atrial fibrillation following a failed AF ablation

IRAS no
239296

Study contact information
Name:
 Debra Dempster
Email: D.Dempster@rbht.nhs.uk

Principal investigator
Dr Tom Wong

Click here for more information


Concomitant epicardial ledt atrial appendage closure and catheter ablation

Study
A study of concomitant epicardial left atrial appendage closure and catheter ablation in treating recurrent persistent atrial fibrillation after failed previous ablation

IRAS no
229383

Study contact information
Name:
 Peng Zhang
Email: p.zhang@rbht.nhs.uk

Principal investigator
Dr Tom Wong

Click here for more information


Catheter versus thoracoscopic surgical ablation in long standing persistent Atrial Fibrillation

Study
Catheter versus thoracoscopic surgical ablation in long standing persistent Atrial Fibrillation - multicentre randomised control trial

IRAS no
155944

Study contact information
Name:
 Paula Rogers
Email: P.Rogers@rbht.nhs.uk

Principal investigator
Dr Tom Wong

Click here for more information


VITAL - The VyronUS Image Then Ablate study

Study
Clinical investigation of the VytronUS Ablation System for Treatment of Symptomatic Drug-refractory Paroxysmal Atrial Fibrillation (VITAL)

IRAS no
230460

Study contact information
Name: Dr Tom Wong
Email: T.Wong2@rbht.nhs.uk

Principal investigator
Dr Tom Wong

Click here for more information


Map Registry of Procedural Long-term Clinical Outcomes

Study
AcQMap® Global Registry of Procedural and Long-term Clinical Outcomes.

IRAS no
258348

Study contact information
Name: Mathew Varghese
Email: M.Varghese@rbht.nhs.uk

Principal investigator
Dr Tom Wong

Click here for more information

The gut microbiome in rheumatoid arthritis and bronchiectasis 

Study
The gut microbiome in rheumatoid arthritis and bronchiectasis

IRAS no
222542

Study contact information
Name:
 Cheyanne Kailla
Email: c.kailla@rbht.nhs.uk

Principal investigator
Dr Rosemary Boyton

Click here for more information


Observational cohort and Biobank UK Study

Study
Observational cohort and Biobank UK Study

IRAS no
173303

Study contact information
Name:
 Najwa Soussi
Email: N.Soussi@rbht.nhs.uk

Principal investigator
Professor Michael Loebinger

Click here for more information


Efficacy and safety of 12 months of therapy with inhaled Promixin (colistimethate sodium)

Study
A double-blind, placebo controlled, multicentre, clinical trial to investigate the efficacy and safety of 12 months of therapy with inhaled Promixin (colistimethate sodium) in the treatment of subjects with non-cystic fibrosis bronchiectasis

IRAS no
213606

Study contact information
Name:
 Najwa Soussi
Email: N.Soussi@rbht.nhs.uk

Principal investigator
Professor Michael Loebinger

Click here for more information


The Clear study

Study
A 2x2 factorial randomised single blind open labelled trial to determine the clinical and cost -effectiveness of hypertonic saline (HTS 6%) and carbocysteine versus usual care over 12 months in non-cystic fibrosis bronchiectasis (BE): The Clear study

IRAS no
214254

Study contact information
Name:
 Najwa Soussi
Email: N.Soussi@rbht.nhs.uk

Principal investigator
Professor Michael Loebinger

Click here for more information


BronchUK: Clinimetric properties of outcome measures in bronchiectasis in the UK

Study
BronchUK: Clinimetric properties of outcome measures in bronchiectasis in the UK

IRAS no 
166832

Study contact information
Name:
 Najwa Soussi
Email: N.Soussi@rbht.nhs.uk

Principal investigator
Professor Michael Loebinger

Click here for more information


The EMBARC European Bronchiectasis Registry

Study
The EMBARC European Bronchiectasis Registry

IRAS no
165833

Study contact information
Name:
 Najwa Soussi
Email: N.Soussi@rbht.nhs.uk

Principal investigator
Professor Michael Loebinger

Click here for more information


The Willow Study

Study
A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multi-Center Study to Assess the Efficacy, Safety and Tolerability, and Pharmacokinetics of INS1007 Administered Once Daily for 24 Weeks in Subjects with Non-Cystic Fibrosis Bronchiectasis

IRAS no
233267

Study contact information
Name:
 Najwa Soussi
Email: N.Soussi@rbht.nhs.uk

Principal investigator
Professor Michael Loebinger

Click here for more information


The BRIDGE study

Study
The BRIDGE study- Bronchiectasis Research Involving Databases, Genomics and Endotyping to match the right treatment to the right patient

IRAS no
228760

Study contact information
Name:
 Najwa Soussi
Email: N.Soussi@rbht.nhs.uk

Principal investigator
Professor Michael Loebinger

Click here for more information


VITAL-BE

Study
A Trial of the Safety, Tolerability and Efficacy of 2 doses of Cayston (Aztreonam Lysine) compared to placebo in participants with bronchiectasis

IRAS no
252929

Study contact information
Name:
 Najwa Soussi
Email: N.Soussi@rbht.nhs.uk

Principal investigator
Professor Michael Loebinger

Click here for more information

Circulating cells in advanced cancer

Study
Sample collection study to explore CIrCulating tumour cells, cell free DNA and leucocytes with ImagesTReam analysis in patients with various

IRAS no
198179

Study contact information
Name: Paula Rogers
Email: p.rogers@rbht.nhs.uk

Principal investigator
Paula Rogers

Click here for more information

RELIEF

Study
A randomised, double-blind, placebo-controlled, crossover, dose escalation study of BLU-5937 in subjects with unexplained or refractory chronic cough

IRAS no
260431

Study contact information
Name: Maria Nunez
Email: m.nunez@rbht.nhs.uk

Principal investigator
Dr James Hull

Click here for more information


CHILO

Study
Inhalation challenge to assess Inducible Laryngeal Obstruction CHILO.

IRAS no
250025

Study contact information
Name: Dr James Hull
Email: j.hull@rbht.nhs.uk

Principal investigator
Dr James Hull

Click here for more information

UK lung volume reduction

Study
UK lung volume reduction - multicentre observational

IRAS no
190196

Study contact information
Name:
 Sara  Buttery
Email: S.Buttery@rbht.nhs.uk

Principal investigator
Dr Nicholas Hopkinson

Click here for more information


Impact of smoking cessation on skeletal muscle atrophy and hypertrophy pathways in COPD

Study
Impact of smoking cessation on skeletal muscle atrophy and hypertrophy pathways in COPD

IRAS no
5020

Study contact information
Name:
 Ahmad Sadaka
Email: A.Sadaka@rbht.nhs.uk

Principal investigator
Dr Nicholas Hopkinson


Microbiome of the lung in patients treated with endobronchial lung volume reduction coils for emphysema

Study
Studying the microbiome of the lung in patients treated with endobronchial lung volume reduction coils for emphysema

IRAS no
215696

Study contact information
Name:
 Dr Justin Garner
Email: J.Garner@rbht.nhs.uk

Principal investigator
Dr Samuel Kemp

Click here for more information


RePneu lung volume reduction coil - European registry

Study
RePneu lung volume reduction coil - European Registry

IRAS no
181479

Study contact information
Name:
 Dr Justin Garner
Email: J.Garner@rbht.nhs.uk

Principal investigator
Dr Samuel Kemp

Click here for more information


NMES in patients with COPD and quadriceps weakness

Study
Quadriceps neuromuscular electrical stimultaion (NMES) as an adjunct to pulmonary rehabilitation in patients with COPD and quadriceps weakness - a randomised double-blind placebo-controlled trial.

IRAS no
234536

Study contact information
Name:
 Sarah Jones
Email: S.Jones5@rbht.nhs.uk

Principal investigator
Dr William Man

Click here for more information


Iron and COPD exercise trial

Study
Iron and Chronic Obstructive Pulmonary Disease (COPD) exercise trial

IRAS no
204579

Study contact information
Name:
 Matt Pavitt
Email: M.Pavitt@rbht.nhs.uk

Principal investigator
Professor Michael Polkey

Click here for more information


Pressure and airflow/volume changes which accompany partial closure of the larynx

Study
An investigation into the pressure and airflow/volume changes which accompany partial closure of the larynx during expiration in patients with Chronic Obstructive Pulmonary Disease (COPD) and the effect of applying a positive end expired pressure 

IRAS no
163863

Study contact information
Name:
 Mike Apps
Email: M.Apps@rbht.nhs.uk

Principal investigator
Professor Michael Polkey

Click here for more information


"REACTION" trial

Study
Identifying responders and exploring mechanisms of action of the endobronchial coil treatment for emphysema (“REACTION”-TRIAL)

IRAS no
179313

Study contact information
Name:
 Dr Justin Garner
Email: J.Garner@rbht.nhs.uk

Principal investigator
Professor Pallav Shah

Click here for more information


Airway microenvironment in patients undergoing surgical and bronchoscopic interventions

Study
Studying the airway microenvironment in patients undergoing surgical and bronchoscopic interventions for COPD

IRAS no
217587

Study contact information
Name:
 Dr Justin Garner
Email: J.Garner@rbht.nhs.uk

Principal investigator
Professor Pallav Shah

Click here for more information


Lung volume reduction in severe emphysema

Study
A single arm pilot study of lung volume reduction in severe emphysema using bronchoscopic autologous blood instillation in combination with intra-bronchial valves

IRAS no
135459

Study contact information
Name:
 Dr Justin Garner
Email: J.Garner@rbht.nhs.uk

Principal investigator
Professor Pallav Shah

Click here for more information


RejuvenAir™ System metered cryospray therapy for Chronic Bronchitis patients

Study
A prospective safety and feasibility study of the RejuvenAir™ System metered cryospray therapy for Chronic Bronchitis patients

IRAS no
185214

Study contact information
Name:
 Dr Justin Garner
Email: J.Garner@rbht.nhs.uk

Principal investigator
Professor Pallav Shah

Click here for more information


The London COPD cohort RSV study

Study
The London COPD cohort respiratory syncytial virus (RSV) study

IRAS no
232292

Study contact information
Name:
 Dexter Wiseman
Email: D.Wiseman@rbht.nhs.uk

Principal investigator
Professor Jadwiga Wedzicha

Click here for more information


The BLF early COPD development partnership grant

Study
The BLF early COPD development partnership grant

IRAS no
206796

Study contact information
Name:
 Ethaar El-Emir
Email: E.El-Emir@rbht.nhs.uk

Principal investigator
Professor Jadwiga Wedzicha

Click here for more information


Relationship between patient phenotypes and exacerbations in chronic obstructive pulmonary disease

Study
Relationship between patient phenotypes and exacerbations in chronic obstructive pulmonary disease

IRAS no
13535

Study contact information
Name:
 Gavin Donaldson
Email: gavin.donaldson@imperial.ac.uk

Principal investigator
Professor Jadwiga Wedzicha


Mechanisms of increased susceptibility to rhinovirus infection

Study
Mechanisms of increased susceptibility to rhinovirus infection in frequent and infrequent exacerbators of Chronic Obstructive Pulmonary Disease

IRAS no
181679

Study contact information
Name:
 Lydia Finney
Email: L.Finney@rbht.nhs.uk

Principal investigator
Professor Jadwiga Wedzicha

Click here for more information


Oxidative metabolism and atrophy in primary human skeletal muscle cell

Study
Primary culture of human skeletal muscle cells from patients with conditions impairing muscle mitochondrial oxidative metabolism and causing muscle atrophy to investigate underlying molecular mechanisms of reduced oxidative metabolism and atrophy and potential novel therapies.

IRAS no
214624

Study contact information
Name:
 Dr Amanda Natanek
Email: A.Natanek@rbht.nhs.uk

Principal investigator
Dr Amanda Natanek

Click here for more information


ELEVATE

Study
A RandomizEd ControlLed Study of PnEumRx Endobronchial Coil System Versus Standard-of-Care Medical MAnagement in the Treatment of Subjects with Severe Emphysema (ELEVATE) A Postmarket Surveillance Study (PMS).

IRAS no
242606

Study contact information
Name: 
Professor Pallav Shah
Email: P.Shah@rbht.nhs.uk 

Principal investigator
Professor Pallav Shah

Click here for more information


Air Pollution in COPD

Study
The Effect of Air Pollution on Small Airway Lung Function in COPD.

IRAS no
260264

Study contact information
Name:
Sally Meah
Email: s.meah@rbht.nhs.uk

Principal investigator
Dr Omar Usmani

Click here for more information


Inhaled SNG001 in COPD patients

Study
A randomised, double-blind, placebo-controlled study, in COPD patients with and without a confirmed respiratory virus infection assessing anti-viral biomarker responses of inhaled SNG001 compared to placebo.

IRAS no
232887

Study contact information
Name:
Dexter Wiseman
Email: D.Wiseman@rbht.nhs.uk

Principal investigator
Professor Jadwiga Wedzicha

Click here for more information


SPACE FOR COPD maintenance

Study
SPACE FOR COPD© delivered as a maintenance programme on Pulmonary Rehabilitation discharge: a randomised controlled trial evaluating the long-term effects on exercise tolerance and mental well-being

IRAS no
262581

Study contact information
Name:
Ruth Barker
Email: R.Barker2@rbht.nhs.uk

Principal investigator
Dr William Man


ESPRESSO

Study
Early Supported discharge with Pulmonary REhabilitation following Severe acute exacerbations of COPD – Safety and Outcomes (ESPRESSO)

IRAS no
269894

Study contact information
Name:
Ruth Barker
Email: R.Barker2@rbht.nhs.uk

Principal investigator
Dr William Man


SHIELD - Singing for Health

Study
Singing for Health: Improving Experience of Lung Disease

IRAS no
259170

Study contact information
Name:
Dr Keir Philip
Email: K.Philip@rbht.nhs.uk

Principal investigator
Dr Nicholas Hopkinson

Click here for more information


AIRFLOW-3

Study
A Multicenter, Randomised, Sham-controlled Study to Evaluate Safety and Efficacy After Treatment with the Nuvaira Lung Denervation System in Subjects with Chronic Obstructive Pulmonary Disease (COPD).

IRAS no
253708

Study contact information
Name:
Dr Francesca Conway
Email: f.conway@rbht.nhs.uk

Principal investigator
Professor Pallav Shah 

Click here for more information

There are currently no active studies 

Heterotaxy and abnormalities in intestinal rotation

Study
Heterotaxy and abnormalities in intestinal rotation

IRAS no
170433

Study contact information
Name:
 Anastasia Fotaki
Email: a.fotaki@rbht.nhs.uk

Principal investigator
Dr Julene Carvalho

Click here for more information


Pharmacokinetics and pharmacodynamics of edoxaban in paediatric patients

Study
A phase 1, open-label, single-dose, non-randomised study to evaluate pharmacokinetics and pharmacodynamics of edoxaban in pediatric patients 

IRAS no
200445

Study contact information
Name:
 Neil West
Email: N.West@rbht.nhs.uk

Principal investigator
Dr Zdenek Slavik

Click here for more information


The experiences of children with a diagnosis, their parents and siblings

Study
How do families experience receiving a positive diagnosis for an inherited cardiac condition for a child: the experiences of children with a diagnosis, their parents and siblings

IRAS no
167395

Study contact information
Name:
 Dr Janice Till
Email: j.till@rbht.nhs.uk

Principal investigator
Dr Janice Till

Click here for more information


Pedometer walking program for ACHD patients

Study
Does a pedometer-based walking programme affect exercise capacity and quality of life in sedentary adults with congenital heart disease?

IRAS no
232271

Study contact information
Name:
 Ms Lynda Shaughnessy
Email: L.Shaughnessy@rbht.nhs.uk

Principal investigator
Ms Lynda Shaughnessy

Click here for more information

Outcome validation in noses of subjects with CF and non-CF volunteers

Study
Outcome validation in noses of subjects with cystic fibrosis and non-CF volunteers

IRAS no
215047

Study contact information
Name:
 Aarash Saleh
Email: a.saleh@rbht.nhs.uk

Principal investigator
Professor Eric Alton

Click here for more information


Living with cystic fibrosis

Study
Living with Cystic fibrosis

IRAS no
196567

Study contact information
Name:
 Olga Archangelidi
Email: o.archangelidi@rbht.nhs.uk

Principal investigator
Dr Siobhan Carr

Click here for more information


CF start

Study
The cystic fibrosis (CF) anti-staphylococcal antibiotic prophylaxis trial (CF START); a randomised registry trial to assess the safety and efficacy of flucloxacillin as a longterm prophylaxis agent for infants with CF

IRAS no
211995

Study contact information
Name:
 Dr Siobhan Carr
Email: s.carr@rbht.nhs.uk

Principal investigator
Dr Siobhan Carr

Click here for more information


MAGIC

Study
Managing abnormal glucose in cystic fibrosis (MAGIC)- the development of a self-management education programme for people with CFRD

IRAS no
215946

Study contact information
Name:
 Sarah Collins
Email: s.collins@rbht.nhs.uk

Principal investigator
Ms Sarah Collins

Click here for more information


Safety and pharmacodynamics of long-term Ivacaftor treatment for CF

Study
A Phase 3, 2-Arm, open-label study to evaluate the safety and pharmacodynamics of long-term Ivacaftor treatment in subjects with Cystic Fibrosis who are less than 24 Months of age at treatment initiation and have a CFTR gating mutation

IRAS no
228921

Study contact information
Name:
 Nicole Westrupp
Email: n.westrupp@rbht.nhs.uk

Principal investigator
Professor Jane Davies

Click here for more information


CLIMB-CF

Study
Clinical monitoring and biomarkers to stratify severity and predict outcomes in children with cystic fibrosis (CLIMB-CF).

IRAS no
207718

Study contact information
Name:
 Nicole Westrupp
Email: n.westrupp@rbht.nhs.uk

Principal investigator
Professor Jane Davies

Click here for more information


Non-invasive detection of pseudomonas aeruginosa lower airway infection in patients with CF

Study
Non-invasive detection of Pseudomonas aeruginosa lower airway infection in patients with Cystic Fibrosis

IRAS no
233578

Study contact information
Name:
 Claire Edmondson
Email: C.Edmondson@rbht.nhs.uk

Principal investigator
Professor Jane Davies

Click here for more information


Safety, pharmacokinetics and pharmacodynamics of Ivacaftor in CF patients (less than 24 months old)

Study
A Phase 3, 2 Part, open-Label study to evaluate the safety, pharmacokinetics, and pharmacodynamics of Ivacaftor in subjects with Cystic Fibrosis who are less than 24 Months of age at treatment initiation and have a CFTR gating mutation

IRAS no
199957

Study contact information
Name:
 Nicole Westrupp
Email: n.westrupp@rbht.nhs.uk

Principal investigator
Professor Jane Davies

Click here for more information


Safety and efficacy of long-term treatment with VX 661 in combination with Ivacaftor

Study
A Phase 3, open label, rollover study to evaluate the safety and efficacy of long term treatment with VX 661 in combination with Ivacaftor in subjects aged 12 years and older with Cystic Fibrosis , homozygous or heterozygous for the F508del CFTR mutation

IRAS no
186033

Study contact information
Name:
 Sandra Scott
Email: S.Scott@rbht.nhs.uk

Principal investigator
Professor Jane Davies

Click here for more information


Multiple breath washout in paediatric chronic airways disease

Study
Multiple Breath Washout in paediatric chronic airways disease: Building a clinimetrics dataset

IRAS no
204190

Study contact information
Name:
 Clare Saunders
Email: C.Saunders2@rbht.nhs.uk

Principal investigator
Professor Jane Davies

Click here for more information


Screening tools for drug-induced ototoxicity in adults with CF

Study
A prospective cross-sectional study analysing the utility of novel tablet-based audiometry and an interactive web-based hearing app as screening tools for drug-induced ototoxicity in adults with cystic fibrosis.

IRAS no
230986

Study contact information
Name:
 Anitha Vijayasingam
Email: A.Vijayasingam@rbht.nhs.uk

Principal investigator
Dr Anand Shah

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Improving outcome measures for physiotherapy trials of airway clearance in adults in CF

Study
Improving outcome measures for physiotherapy trials of airway clearance in adults with CF

IRAS no
154635

Study contact information
Name:
 Gemma Stanford
Email: G.Stanford@rbht.nhs.uk

Principal investigator
Dr Nicholas Simmonds

Click here for more information


Finger-prick capillary blood sampling in chronic lung disease

Study
Single-centre validation of finger-prick capillary blood sampling for remote monitoring in chronic lung disease including antifungal therapeutic drug monitoring.

IRAS no
239814

Study contact information
Name:
 Professor Michael Loebinger 
Email: M.Loebinger@rbht.nhs.uk

Principal investigator
Professor Michael Loebinger 

Click here for more information


Lenabasum in Cystic Fibrosis

Study
A Multicenter, Randomised, Double-Blind, Placebo-Controlled Phase 2 Trial to Evaluate Efficacy and Safety of Lenabasum in Cystic Fibrosis.

IRAS no
242168

Study contact information
Name:
 Dr Andrew Jones
Email: A.Jones2@rbht.nhs.uk

Principal investigator
Dr Andrew Jones

Click here for more information


VX17-661-116

Study
A Phase 3, Open-label, Rollover Study to Evaluate the Safety and Efficacy of Long-term Treatment With Tezacaftor in Combination With Ivacaftor in Subjects With Cystic Fibrosis Aged 6 Years and Older, Homozygous or Heterozygous for the F508del-CFTR Mutation.

IRAS no
241643

Study contact information
Name:
 Professor Jane Davies
Email: J.Davies@rbht.nhs.uk

Principal investigator
Professor Jane Davies

Click here for more information


VX17-659-105 Open-label Safety and Efficacy of VX-659 in CF

Study
A Phase 3, Open-label Study Evaluating the Long-term Safety and Efficacy of VX-659 Combination Therapy in Subjects with Cystic Fibrosis Who Are Homozygous or Heterozygous for the F508del Mutation.

IRAS no
241641

Study contact information
Name:
 Dr Nicholas Simmonds
Email: N.Simmonds@rbht.nhs.uk

Principal investigator
Dr Nicholas Simmonds

Click here for more information


MR assessment of shunt fraction in CF patients before and after BAE

Study
A prospective pilot study: Magnetic Resonance Imaging (MRI) derived measures of bronchial arterial flow in the assessment and follow-up of patients with Cystic fibrosis (CF) who undergo bronchial artery embolisation.

IRAS no
256039

Study contact information
Name:
 Bhavin Rawal
Email: B.Rawal@rbht.nhs.uk

Principal investigator
Professor Simon Padley


Organoid Study (HIT-CF)

Study
Stratifying Cystic Fibrosis Patients Based on Intestinal Organoid Response To Different CFTR-modulators

IRAS no
255704

Study contact information
Name:
 Maria Nunez
Email: M.Nunez@rbht.nhs.uk

Principal investigator
Dr Nicholas Simmonds


Phase IIa study of PC945 in Aspergillosis in Cystic Fibrosis patients

Study
An open-label study to assess the safety, pharmacokinetics and pharmacodynamics of inhaled PC945 in adult Cystic Fibrosis (CF) patients with persistent pulmonary Aspergillus fumigatus infection

IRAS no
248009

Study contact information
Name:
 Dr Sandra Scott
Email: s.scott@rbht.nhs.uk

Principal investigator
Dr Nicholas Simmonds

Click here for more information


Exercise behaviours in children and young people with cystic fibrosis

Study
Identifying predictors for maintenance of exercise participation in children and young people with cystic fibrosis.

IRAS no
246187

Study contact information
Name:
Nicky Murray
Email: N.Murray@rbht.nhs.uk

Principal investigator
Nicky Murray

Click here for more information


HIT-CF Organoid Study

Study
Part 1 HIT-CF Project: Stratifying Cystic Fibrosis Patients Based on Intestinal Organoid Response To Different CFTR-modulators

IRAS no
255074

Study contact information
Name:
Maria Nunez
Email: M.Nunez@rbht.nhs.uk

Principal investigator
Dr Nicholas Simmonds


Measurement of novel indices of lung function in respiratory disease

Study
Measurement of novel indices of lung function in respiratory disease

IRAS no
208382

Study contact information
Name:
Clare Saunders
Email: C.Saunders2@rbht.nhs.uk

Principal investigator
Professor Jane Davies

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A dose finding study in patients aged 12 and above with cystic fibrosis using the Respimat® inhaler

Study
A randomised, double-blind, placebo-controlled and parallel group trial to evaluate efficacy and safety of twice daily inhaled doses of BI 1265162 delivered by Respimat® inhaler as add-on therapy to standard of care over 4 weeks in patients with cystic fibrosis

IRAS no
263830

Study contact information
Name:
 Dr Sandra Scott
Email: s.scott@rbht.nhs.uk

Principal investigator
Professor Jane Davies


A study of the combined effects of three CFTR modulator medicines in people with cystic fibrosis aged 12 and older

Study
A Phase 3 study of the long-term safety of a triple combination therapy of VX-445, tezacaftor and ivacaftor in people with cystic fibrosis aged 12 and older.

IRAS no
269907

Study contact information
Name:
 Dr Sandra Scott
Email: s.scott@rbht.nhs.uk

Principal investigator
Dr Nicholas Simmonds


A study to learn more about a combination of CFTR modulator medicines in people with Cystic Fibrosis (VX 18 445 104)

Study
A study to evaluate the effectiveness and safety of VX 445/Tezacaftor/Ivacaftor in people with Cystic Fibrosis who are heterozygous for the F508del mutation and a gating or residual function mutation.

IRAS no
268820

Study contact information
Name:
 Dr Sandra Scott
Email: s.scott@rbht.nhs.uk

Principal investigator
Professor Jane Davies

There are currently no active studies 

Ilprost (Ventavis) in patients with Eisenmenger syndrome

Study
A single-centre, placebo-controlled, double-blinded, randomized, crossover study of Iloprost (Ventavis®) in patients with Eisenmenger syndrome

IRAS no
121948

Study contact information
Name:
 Dr Stephen John Wort
Email: s.wort@rbht.nhs.uk

Principal investigator
Dr Stephen John Wort

Click here for more information

Molecular genetics of human birth defects

Study
Molecular genetics of human birth defects – mapping and gene identification

IRAS no
103488

Study contact information
Name:
 Dr Claire Hogg
Email: c.hogg@rbht.nhs.uk

Principal investigator
Dr Claire Hogg


Genetic linkage evaluation in inherited cardiac conditions

Study
Genetic linkage evaluation in inherited cardiac conditions

IRAS no
53663

Study contact information
Name:
 Dr Janice Till
Email: j.till@rbht.nhs.uk

Principal investigator
Dr Janice Till


ARRY-371797 (p38 MAP Kinase Inhibitor)

Study
A Phase 3, multinational, randomised, placebo-controlled study of ARRY-371797 in patients with Symptomatic Dilated Cardiomyopathy due to a Lamin A/C Gene Mutation

IRAS no
254544

Study contact information
Name: Dr James Ware
Email: J.Ware@rbht.nhs.uk

Principal investigator
Dr James Ware

Click here for more information

CardioMEMS Heart Failure System

Study
CardioMEMS Heart Failure System 

IRAS no
219676

Study contact information
Name:
 Angela Gallagher
Email: a.gallagher2@rbht.nhs.uk

Principal investigator
Professor Martin Cowie

Click here for more information


Factors influencing physical activity among individuals living with heart failure

Study
Factors influencing physical activity among individuals living with heart failure: a mixed-methods study

IRAS no
205050

Study contact information
Name:
 Professor Martin Cowie
Email: m.cowie@rbht.nhs.uk

Principal investigator
Professor Martin Cowie

Click here for more information


HFpEF in patients assessed for Sleep Disordered Breathing

Study
Prevalence and prognosis of Heart Failure with Preserved Ejection Fraction (HFpEF) in patients assessed for Sleep Disordered Breathing

IRAS no
228728

Study contact information
Name:
 Angela Gallagher
Email: a.gallagher2@rbht.nhs.uk

Principal investigator
Professor Martin Cowie

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Assessing organisational readiness for heart failure remote monitoring

Study
Assessing Organisational Readiness for Heart Failure Remote Monitoring

IRAS no
236418

Study contact information
Name:
 Darshan Brahmbhatt
Email: d.brahmbhatt@rbht.nhs.uk

Principal investigator
Professor Martin Cowie

Click here for more information


BAROSTIM NEO

Study
BAROSTIM NEO ® - Baroreflex Activation Therapy® for Heart Failure

IRAS no
235110

Study contact information
Name:
 Ms Rebecca Lane
Email: r.lane@rbht.nhs.uk

Principal investigator
Ms Rebecca Lane

Click here for more information


IRONMAN

Study
Effectiveness of intravenous iron treatment vs standard care in patients with heart failure and iron deficiency: a randomised, open-label multicentre trial (IRONMAN)

IRAS no
191168

Study contact information
Name:
 Peng Zhang
Email: p.zhang@rbht.nhs.uk

Principal investigator
Ms Rebecca Lane

Click here for more information


The effects of inorganic nitrite on cardiac and skeletal muscle

Study
The Effects of inorganic nitrite on cardiac and skeletal muscle: Physiology, pharmacology, and therapeutic potential in patients with Chronic Heart Failure

IRAS no
87162

Study contact information
Name:
 Brodie Loudon
Email: B.Loudon@rbht.nhs.uk

Principal investigator
Dr Sanjay Prasad

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Mitraclip device in heart failure

Study
Randomised investigation of the Mitraclip device in heart failure: 2nd trial in patients with clinically significant functional mitral regurgitation

IRAS no
220456

Study contact information
Name:
 Joanne Benton
Email: j.benton@rbht.nhs.uk

Principal investigator
Dr Robert Smith

Click here for more information


LCZ696 in paediatric patients

Study
Multicenter, open-label, single dose study to evaluate the safety, tolerability and pharmacokinetics of LCZ696 followed by randomised, double-blind, parallel group,active-controlled study to evaluate the efficacy and safety of LCZ696 in pediatric patients

IRAS no
206351

Study contact information
Name:
 Dr Piers Daubeney
Email: p.daubeney@rbht.nhs.uk

Principal investigator
Dr Piers Daubeney

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AccuCinch® Ventriculoplasty System for Functional Mitral Regurgitation

Study
Safety and performance evaluation of the AccuCinch® Ventricular Repair System for the treatment of heart failure with or without Functional Mitral Regurgitation due to Dilated Ischaemic or Non-Ischaemic Cardiomyopathy. 

IRAS no
230127

Study contact information
Name: Lauren Kelly
Email: L.Kelly2@rbht.nhs.uk

Principal investigator
Dr Robert Smith

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OHCA Risk Scoring

Study
A simple risk scoring system to predict outcome in patients with out-of-hospital cardiac arrest. 

IRAS no
246483

Study contact information
Name: Dr Robert Smith
Email: R.Smith@rbht.nhs.uk

Principal investigator
Dr Robert Smith

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The AMBITION

Study
Assessing mitochondrial bioenergetics in coronary heart disease; correlating cardiac magnetic resonance with the molecular processes that underpin myocardial dysfunction and left ventricular reverse remodelling.

IRAS no
247881

Study contact information
Name: Dr Richard Jones
Email: r.jones@rbht.nhs.uk

Principal investigator
Dr Sanjay Prasad


The REMIT-DCM study

Study
Reverse rEmodelling Markers In the serial evaluation of recenTonset Dilated CardioMyopathy

IRAS no
262962

Study contact information
Name: Dr Daniel Hammersley
Email: d.hammersley@rbht.nhs.uk

Principal investigator
Dr Sanjay Prasad

Click here for more information


PiCSO-AMI-I

Study
Pressure-controlled Intermittent Coronary Sinus Occlusion (PiCSO) in Acute Myocardial Infarction (PiCSO-AMI-I)

IRAS no
259683

Study contact information
Name: Paula Rogers
Email: p.rogers@rbht.nhs.uk

Principal investigator
Dr Charles Ilsley

Click here for more information


Go DCM

Study
Defining the genetics, biomarkers and outcomes for dilated cardiomyopathy: a prospective multi-centre observational study

IRAS no
237880

Study contact information
Name: Teijo Palovaara
Email: T.Palovaara@rbht.nhs.uk

Principal investigator
Dr James Ware


ORBITA-2

Study
A placebo-controlled trial of percutaneous coronary intervention for the relief of stable angina

IRAS no
242451

Study contact information
Name: Meriel Woodruff
Email: M.Woodruff@rbht.nhs.uk

Principal investigator
Dr Vasileios Panoulas

Click here for more information


A trial of cardiac injections of iMP cells during CABG surgery (V1)

Study
A Phase IIB, Randomised, Double-Blinded, Placebo-Controlled Study of the Efficacy and Safety of Intramyocardial Injection of Allogeneic Human Immunomodulatory Progenitor (iMP) cells in Patients Undergoing Coronary Artery Bypass Graft (CABG) Surgery.

IRAS no
226737

Study contact information
Name: Kevin Kirby
Email: K.Kirby@rbht.nhs.uk

Principal investigator
Dr Ali Vazir

Click here for more information


Sanofi Drug Utilisation Study of alirocumab

Study
A drug utilization study (DUS) of alirocumab in Europe to assess the effectiveness of the dosing recommendation to avoid very low LDL-C levels.

IRAS no
245146

Study contact information
Name: Paula Rogers
Email: p.rogers@rbht.nhs.uk

Principal investigator
Dr Barbir Mahmoud

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GSK3008348 in IPF patients using PET imaging

Study
A study of single doses to evaluate the safety, tolerability, pharmacokinetics and target engagement of nebulised GSK3008348 in Idiopathic Pulmonary Fibrosis patients, using positron emission tomography (PET) imaging

IRAS no
221453

Study contact information
Name:
 Lyn Paul
Email: L.Paul@rbht.nhs.uk

Principal investigator
Professor Toby Maher

Click here for more information


Muscle stimulation in advanced idiopathic pulmonary fibrosis (MUST-IPF)

Study
Neuromuscular electrical stimulation (NMES) is a portable hand-held muscle stimulator which allows the thigh muscles to be exercised whilst seated. The aims of this study are to 1) investigate whether NMES is acceptable to patients with IPF and healthcare/research staff and 2) identify if it can improve leg muscle strength and walking ability.

IRAS no
241055

Study contact information 
Name: 
Claire Nolan
Email: c.nolan@rbht.nhs.uk

Principal investigator
Dr William Man

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A study to evaluate to efficacy and safety of BG00011

Study
A randomised, double-blind, placebo-controlled study to evaluate the efficacy and safety of BG00011 in patients with Idiopathic Pulmonary Fibrosis. 

IRAS no
248312

Study contact information
Name: Lyn Paul
Email: l.paul@rbht.nhs.uk

Principal investigator
Professor Toby Maher

Click here for more information


MADIET (version 1.6)

Study
An open label phase IV, multicentre, international, interventional study to evaluate the effect of diet on gastrointestinal adverse events in patients with IPF treated with pirfenidone. 

IRAS no
245949

Study contact information
Name: Dr Elizabeth Renzoni
Email: E.Renzoni@rbht.nhs.uk

Principal investigator
Dr Elizabeth Renzoni

Click here for more information


BI1015550 and nintedanib or pirfenidone in IPF

Study
Safety, tolerability, and pharmacokinetics of multiple rising oral doses of BI 1015550 in patients with idiopathic pulmonary fibrosis (IPF) on no background anti-fibrotic (Part 1) and safety and tolerability of BI 1015550 on top of Nintedanib and Pirfenidone (Part 2). 

IRAS no
239042

Study contact information
Name: Dr Philip Molyneaux
Email: P.Molyneaux@rbht.nhs.uk

Principal investigator
Dr Philip Molyneaux

Click here for more information


GLPG1690 with Standard Treatment in Idiopathic Pulmonary Fibrosis

Study
A Phase 3, randomized, double-blind, parallel-group, placebo controlled multicenter study to evaluate the efficacy and safety of two doses of GLPG1690 in addition to local standard of care for minimum 52 weeks in subjects with idiopathic pulmonary fibrosis. 

IRAS no
254823

Study contact information
Name: Deirdre Flannery
Email: D.Flannery@rbht.nhs.uk

Principal investigator
Dr Philip Molyneaux

Click here for more information


Nintedanib in PF-ILD (extension)

Study
An open-label extension trial of the long-term safety of nintedanib in patients with Progressive Fibrosing Interstitial Lung Disease (PF-ILD)

IRAS no
252018

Study contact information
Name: Lyn Paul
Email: l.paul@rbht.nhs.uk

Principal investigator
Professor Toby Maher

Click here for more information


SCENIC Trial

Study
Randomised, Double-Blind, Placebo-Controlled, Dose-Ranging, Efficacy and Safety Study with Inhaled RVT-1601 for the Treatment of Persistent Cough in Patients with Idiopathic Pulmonary Fibrosis (IPF): SCENIC Trial

IRAS no
260487

Study contact information
Name: Ajerico Del Rosario
Email: A.Delrosario@rbht.nhs.uk

Principal investigator
Professor Toby Maher


TR12 Ph 2 Study in Idiopathic Pulmonary Fibrosis-Nalbuphine ER Tablets

Study
A phase 2, double-blind, randomised, placebo-controlled, two-treatment, two-period crossover efficacy and safety study in Idiopathic Pulmonary Fibrosis (IPF) with Nalbuphine ER tablets for the treatment of cough.

IRAS no
262846

Study contact information
Name: Lyn Paul
Email: l.paul@rbht.nhs.uk

Principal investigator
Professor Toby Maher


GALACTIC-1 Phase 2b study in idiopathic pulmonary fibrosis

Study
GALACTIC-1 - A randomized, double-blind, multicentre, parallel, placebo controlled Phase 2b study in subjects with idiopathic pulmonary fibrosis (IPF) investigating the efficacy and safety of TD139, an inhaled galectin-3 inhibitor administered via a dry powder.

IRAS no
257627

Study contact information
Name: Lyn Paul
Email: l.paul@rbht.nhs.uk

Principal investigator
Dr Philip Molyneaux

CMR sequences for future clinical use

Study
Development of Cardiovascular Magnetic Resonance (CMR) sequences for future clinical use

IRAS no
33773

Study contact information
Name:
 Andy Scott
Email: a.scott07@imperial.ac.uk

Principal investigator
Professor David Firmin


Diffusion tensor CMR imaging of the myocardium

Study
Diffusion Tensor Cardiovascular Magnetic Resonance Imaging of the myocardium

IRAS no
136441

Study contact information
Name:
 Zohya Khalique
Email: Z.Khalique@rbht.nhs.uk

Principal investigator
Professor Dudley Pennell

Click here for more information

Transmural myocardial perfusion with hypertension, HCM and HCM phenocopies with CMR

Study
The measurement of transmural myocardial perfusion in normal subjects and patients with hypertension, hypertrophic cardiomyopathy (HCM) and HCM phenocopies with Cardiovascular Magnetic Resonance (CMR)

IRAS no
171258

Study contact information
Name:
 Brian Halliday
Email: B.Halliday@rbht.nhs.uk

Principal investigator
Dr Sanjay Prasad


Lifestyle and exercise in Hypertrophic Cardiomyopathy

Study
Lifestyle and exercise in Hypertrophic Cardiomyopathy

IRAS no
205294

Study contact information
Name:
 Carmen Chan
Email: L.Chan2@rbht.nhs.uk

Principal investigator
Dr James Ware

Click here for more information

The DEPICT study

Study
Critically ill children and young people: Do national differences in access to emergency paediatric Intensive Care and care during transport affect clinical outcomes and patient experience? The DEPICT study

IRAS no
218569

Study contact information
Name:
 Angela Aramburo
Email: a.aramburocaragol@rbht.nhs.uk

Principal investigator
Ms Angela Aramburo


Rovaroxaban regimen in children with acute venous thromboembolism

Study
Multicentre, open-label, active-controlled, randomized study to evaluate the efficacy and safety of an age and body weight-adjusted rivaroxaban regimen in children with acute venous thromboembolism

IRAS no
155345

Study contact information
Name:
 Helena Sampaio
Email: m.fernandessampaio@rbht.nhs.uk

Principal investigator
Ms Angela Aramburo

Click here for more information


The SANDWICH trial

Study
Sedation and weaning in children: the SANDWICH trial

IRAS no
209448

Study contact information
Name:
 Helena Sampaio
Email: m.fernandessampaio@rbht.nhs.uk

Principal investigator
Ms Angela Aramburo

Click here for more information


S-CAP study

Study
A molecular toolkit for the microbial investigation of severe community acquired pneumonia (S-CAP Study)

IRAS no
189915

Study contact information
Name:
 Natalie Dormand
Email: N.Dormand@rbht.nhs.uk

Principal investigator
Dr Brijesh Patel

Click here for more information


Haemostatic markers in ECMO (HAE) study

Study
Prospective cohort study of haemostatic activation markers and correlation with bleeding and thrombotic complications in patients receiving extracorporeal membrane oxygenation(ECMO)

IRAS no
235036

Study contact information
Name:
 Dr Deepa Arachchillage
Email: D.JayakodyArachchillage@rbht.nhs.uk

Principal investigator
Dr Deepa Arachchillage

Click here for more information


WAVE study - Weaning Algorithms for mechanical VEntilation

Study
Weaning from mechanical ventilation: comparison of open-loop decision support system and routine care in cardiothoracic patients.

IRAS no
239144

Study contact information
Name:
 Dr Brijesh Patel
Email: B.Patel4@rbht.nhs.uk

Principal investigator
Dr Brijesh Patel

Click here for more information


EAT-PK

Study
Does Extra-Corporeal Membrane Oxygenation alter anti-infectives therapy pharmacokinetics in adult critically ill patients?

IRAS no
228196

Study contact information
Name:
 Dr Anna Reed
Email: A.Reed@rbht.nhs.uk

Principal investigator
Dr Anna Reed

Click here for more information


STARRT-AKI

Study
STandard versus Accelerated initiation of Renal Replacement Therapy in Acute Kidney Injury (STARRT-AKI): A Multi-Centre Randomized Controlled Trial.

IRAS no
191390

Study contact information
Name:
 Claire Prendergast
Email: C.Prendergast2@rbht.nhs.uk

Principal investigator
Dr Clara Hernandez Caballero

Click here for more information


Bleeding and thrombotic complications in ECMO and CPB patients

Study
Retrospective cohort study of bleeding and thrombotic complications in patients received extracorporeal membrane oxygenation (ECMO) compared to cardiopulmonary bypass (CPB)

IRAS no
244283

Study contact information
Name:
 Dr Deepa Arachchillage
Email: D.JayakodyArachchillage@rbht.nhs.uk

Principal investigator
Dr Deepa Arachchillage

"Unclassifiable" ILD

Study
Phase II study of Pirfenidone vs placebo in patients with fibrotic ILD that cannot be classified with moderate or high confidence into any other category of fibrotic IP by Multidisciplinary Team (MDT) review (“unclassifiable” ILD).

IRAS no
218417

Study contact information
Name:
 Vladimir Domi
Email: V.Domi@rbht.nhs.uk

Principal investigator
Professor Toby Maher

Click here for more information


Systemic sclerosis associated with ILD

Study
A double blind, randomized, placebo-controlled trial evaluating efficacy and safety of oral nintedanib, 150 mg twice daily for 52 weeks (with follow up until last patient out up to a maximum of 2 years) in patients with systemic sclerosis associated interstitial lung disease

IRAS no
185104

Study contact information
Name:
 Deirdre Flannery
Email: D.Flannery@rbht.nhs.uk

Principal investigator
Professor Toby Maher

Click here for more information


RA associated ILD with UIP pattern

Study
A 52 week, double blind, randomised, placebo-controlled trial evaluating the effect of Nintedanib, 150 mg twice daily, on annual rate of decline in Forced Vital Capacity and safety in patients with RA associated ILD with UIP pattern

IRAS no
217658

Study contact information
Name:
 Vladimir Domi
Email: V.Domi@rbht.nhs.uk

Principal investigator
Professor Toby Maher

Click here for more information


Rituximab vs intravenous cyclophosphamide in connective tissue disease associated ILD

Study
A randomised, double blind controlled trial comparing rituximab against intravenous cyclophosphamide in connective tissue disease associated interstitial lung disease

IRAS no
98339

Study contact information
Name:
 Vladimir Domi
Email: V.Domi@rbht.nhs.uk

Principal investigator
Professor Toby Maher

Click here for more information


Pathogenesis of fibrotic lung disease

Study
Control subjects for better understanding of pathogenesis of fibrotic lung disease

IRAS no
139113

Study contact information
Name:
 Vladimir Domi
Email: V.Domi@rbht.nhs.uk

Principal investigator
Professor Toby Maher

Click here for more information


Pathogenesis and clinical manifestations of pulmonary fibrosis

Study
Pathogenesis and clinical manifestations of pulmonary fibrosis in (A) Connective Tissue Diseases (CTD), (B) Granulomatous Conditions (GC), and (C) Idiopathic Interstitial Pneumonias (IIP)

IRAS no
125496

Study contact information
Name:
 Professor Athol Wells
Email: rbhild@rbht.nhs.uk

Principal investigator
Professor Athol Wells

Click here for more information


Open label extension study of nintedanib in SSc-ILD

Study
An open-label extension trial to assess the long term safety of nintedanib in patients with ‘Systemic Sclerosis associated Interstitial Lung Disease’ (SSc-ILD)

IRAS no
235678

Study contact information
Name:
 Professor Toby Maher
Email: T.Maher@rbht.nhs.uk

Principal investigator
Professor Toby Maher

Click here for more information


TRAIL1

Study
A Randomised, Double-Blind, Placebo-Controlled, Phase 2 Study of Safety, Tolerability and Efficacy of Pirfenidone in Patients with Rheumatoid Arthritis Interstitial Lung Disease

IRAS no
220334

Study contact information
Name:
 Professor Toby Maher
Email: T.Maher@rbht.nhs.uk

Principal investigator
Professor Toby Maher

Click here for more information


Deep learning for HRCT classification of fibrotic lung disease

Study
Deep learning for HRCT classification of fibrotic lung disease

IRAS no
234527

Study contact information
Name:
 Professor Toby Maher
Email: T.Maher@rbht.nhs.uk

Principal investigator
Professor Toby Maher

Click here for more information


Historical exposures in hypersensitivity pneumonitis

Study
A case-referent study of the exposure history of adults with hypersensitivity pneumonitis

IRAS no
245417

Study contact information
Name:
 Dr Johanna Feary
Email: J.Feary@rbht.nhs.uk 

Principal investigator
Dr Johanna Feary

Click here for more information


FIBRINOX

Study
Fibrotic Interstitial Lung Disease and nocturnal oxygen - An observational study of the effects of nocturnal hypoxaemia on patients with fibrotic interstitial lung disease

IRAS no
234305

Study contact information
Name:
 Richard Mordi
Email: R.Mordi@rbht.nhs.uk

Principal investigator
Dr Philip Molyneaux

Click here for more information

Genetic determinants of Kawasaki disease

Study
Genetic determinants of Kawasaki disease for susceptibility and outcome

IRAS no
115933

Study contact information
Name:
 Dr Rodney Franklin
Email: r.franklin@rbht.nhs.uk

Principal investigator
Dr Rodney Franklin

Click here for more information

Tracking no small cell lung cancer evaluation

Study
Tracking non small cell lung cancer evolution through therapy (Rx)

IRAS no
138871

Study contact information
Name:
 Paulo De Sousa
Email: P.DeSousa@rbht.nhs.uk

Principal investigator
Mr Eric Lim

Click here for more information


Video assisted thoracoscopic lobectomy vs conventional Open LobEcTomy

Study
Video assisted thoracoscopic lobectomy versus conventional Open LobEcTomy for lung cancer, a multi-centre randomised controlled trial with an internal pilot

IRAS no
163516

Study contact information
Name:
 Paulo De Sousa
Email: P.DeSousa@rbht.nhs.uk

Principal investigator
Mr Eric Lim

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Cancer recurrence in patients after lung cancer surgery

Study
The process of disclosure of the risk of cancer recurrence in patients following potentially curative lung cancer surgery: a multiple case study

IRAS no
168907

Study contact information
Name:
 Matthew Johnson
Email: M.Johnson@rbht.nhs.uk

Principal investigator
Mr Eric Lim

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Cancer research UK stratified medicine programme

Study
The Cancer Research UK stratified medicine programme: Pilot Study

IRAS no
74277

Study contact information
Name:
 Professor Andrew Nicholson
Email: a.nicholson@rbht.nhs.uk

Principal investigator
Professor Andrew Nicholson

There are currently no active studies 

RAPID NSTEMI

Study
A randomised controlled trial of very early angiography +/- intervention versus standard of care on outcomes in patients with non ST-elevation myocardial infarction. 

IRAS no
233921

Study contact information
Name: Dr Miles Dalby
Email: M.Dalby@rbht.nhs.uk

Principal investigator
Dr Miles Dalby

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Diffusion Tensor Imaging in ST-elevation Myocardial Infarction

Study
Investigation of Post-Myocardial Infarction Left Ventricular Remodelling  By Diffusion Tensor Cardiac Magnetic Resonance

IRAS no
259868

Study contact information
Name: Paula Rogers
Email: p.rogers@rbht.nhs.uk

Principal investigator
Dr Ranil De Silva


Infarction NSTEMI v1.0

Study
Non-ST-segment elevation myocardial infarction Registry.

IRAS no
261605

Study contact information
Name: Paula Rogers
Email: p.rogers@rbht.nhs.uk

Principal investigator
Dr Vasileios Panoulas

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Pulmonary Non-Tuberculous Mycobacterial Disease

Study
A molecular approach to the diagnosis, assessment, monitoring and treatment of pulmonary non-Tuberculous Mycobacterial Disease.

IRAS no
212193

Study contact information
Name:
 Huw Ellis
Email: Huw.Ellis@rbht.nhs.uk

Principal investigator
Dr Michael Loebinger

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OPTIMA

Study
An open-label, non-controlled, multicentre, pilot clinical trial of inhaled Molgramostim in subjects with antibiotic-resistant non-tuberculosis mycobacterial (NTM) infection - OPTIMA

IRAS no
238305

Study contact information
Name:
 Najwa Soussi
Email: N.Soussi@rbht.nhs.uk

Principal investigator
Dr Michael Loebinger

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LAI in adult patients with NTM lung infections caused by MAC

Study
An open-label safety extension study to a multicenter study of liposomal amikacin for inhalation (LAI) in adult patients with non-Tuberculous Mycobacterial (NTM) lung infections caused by Mycobacterium avium complex (MAC) that are refractory to treatment

IRAS no
190666

Study contact information
Name:
 Najwa Soussi
Email: N.Soussi@rbht.nhs.uk

Principal investigator
Dr Michael Loebinger

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There are currently no active studies 

NEURO-PACK

Study
NEURO-PACK: Neurologic prognosis after cardiac arrest in kids. An observational study of neurodevelopmental outcome after cardiac arrest in children admitted to paediatric intensive care

IRAS no
223292

Study contact information
Name:
 Dr Sandra Gala-Peralta
Email: s.gala-peralta@rbht.nhs.uk

Principal investigator
Dr Sandra Gala-Peralta

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Phase 3 - Edoxaban DU-176b in children

Study
An open-label randomized, parallel-group, multicenter, observational trial to evaluate the safety and efficacy of edoxaban tosylate in children from 38 weeks gestational age to less than 18 years of age with cardiac disease at risk of thromboembolic events.

IRAS no
238090

Study contact information
Name:
 Dr Piers Daubeney
Email: P.Daubeney@rbht.nhs.uk

Principal investigator
Dr Piers Daubeney

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Remote monitoring & gaming technology for children with CF

Study
Project Fizzyo: Remote monitoring and gaming technology for improving physiotherapy prescription, adherence and prediction of clinical outcomes in children with cystic fibrosis.

IRAS no
228625

Study contact information
Name:
 Ms Nicky Murray
Email: N.Murray@rbht.nhs.uk

Principal investigator
Ms Nicky Murray

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Novel electronic monitoring devices to monitor adherence in asthma

Study
A feasibility study to assess Novel Electronic Monitoring Devices (NEDM) for monitoring adherence in children with asthma.

IRAS no
239759

Study contact information
Name:
 Dr Louise Fleming
Email: L.Fleming@rbht.nhs.uk

Principal investigator
Dr Louise Fleming

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Severe Paediatric Asthma Collaborative in Europe (SPACE)

Study
Severe Paediatric Asthma Collaborative in Europe (SPACE).

IRAS no
230893

Study contact information
Name:
 Dr Louise Fleming
Email: L.Fleming@rbht.nhs.uk

Principal investigator
Dr Louise Fleming

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Fevipiprant

Study
A multicenter, open-label, 8 day treatment study to assess the pharmacokinetics, safety and tolerability of fevipiprant delivered via a once daily chewable tablet in children aged 6 to <12 years with asthma

IRAS no
264789

Study contact information
Name:
 Yvonne Bingham
Email: Y.Bingham@rbht.nhs.uk

Principal investigator
Dr Louise Fleming


Microbial ecology effects relating to childhood asthma (MEERCAT)

Study
Impact of premature birth on the gastrointestinal microbiota in early infancy and respiratory health at school age: a comparison of premature and term birth cohorts.

IRAS no
251418

Study contact information
Name:
 Yvonne Bingham
Email: Y.Bingham@rbht.nhs.uk

Principal investigator
Professor Sejal Saglani


A study of the combined effects of three CFTR modulator medicines in children with cystic fibrosis aged 6 to 11 (VX18-445-106)

Study
A Phase 3 study of the efficacy, safety and the body’s effects on a triple combination therapy of VX-445, tezacaftor and ivacaftor in children with cystic fibrosis aged 6 to 11

IRAS no
269510

Study contact information
Name:
 Sandra Scott
Email: s.scott@rbht.nhs.uk

Principal investigator
Professor Jane Davies

Unexplained respiratory muscle weakness or respiratory failure

Study
Prevalence of Pompe’s disease amongst patients with unexplained respiratory muscle weakness or respiratory failure

IRAS no
184294

Study contact information
Name:
 Mike Apps
Email: M.Apps@rbht.nhs.uk

Principal investigator
Professor Michael Polkey

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MRI in the assessment of CF and primary ciliary dyskinesia

Study
Use of MRI in the assessment of cystic fibrosis and primary ciliary dyskinesia - A clinical feasibility study

IRAS no
196228

Study contact information
Name:
 Dr Anand Devaraj
Email: a.devaraj@rbht.nhs.uk

Principal investigator
Dr Anand Devaraj

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Machine learning to diagnose PCD

Study
Improving Primary Ciliary Dyskinesia diagnosis using artificial intelligence

IRAS no
259067

Study contact information
Name:
 Thomas Burgoyne
Email: T.Burgoyne@rbht.nhs.uk

Principal investigator
Professor Claire Hogg


IN-PCD

Study
The Effects of Inhaled Corticosteroids on Inflammation and Infection in Primary Ciliary Dyskinesia.

IRAS no
256504

Study contact information
Name:
 Laura Gardner
Email: L.Gardner@rbht.nhs.uk

Principal investigator
Professor Jane Davies

Heart rate reduction in PH using pressure volume loop analysis

Study
Evaluation of right ventricular performance in response to heart rate reduction in pulmonary hypertension using pressure volume loop analysis at rest and on exercise

IRAS no
219677

Study contact information
Name:
 Dr Colm McCabe
Email: c.mccabe2@rbht.nhs.uk

Principal investigator
Dr Colm McCabe

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INOvation-1

Study
A phase 3, placebo controlled, double-blind, randomized, clinical study to determine efficacy, safety and tolerability of pulsed, inhaled nitric oxide (iNO) versus placebo in symptomatic subjects with pulmonary arterial hypertension (PAH): INOvation-1

IRAS no
202601

Study contact information
Name:
 Mahitha Gummadi
Email: M.Gummadi@rbht.nhs.uk

Principal investigator
Dr Stephen John Wort

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PDE-5i

Study
A prospective, randomised, international, multicenter, double-arm, controlled, open-label study of Riociguat in patients with pulmonary arterial hypertension (PAH) who are on a stable dose of phosphodiesterase-5 inhibitors (PDE-5i)

IRAS no
213242

Study contact information
Name:
 Rosa DaCosta
Email: R.DaCosta@rbht.nhs.uk

Principal investigator
Dr Stephen John Wort

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Patients with pulmonary vascular disease

Study
Prospective study in patients with pulmonary vascular disease

IRAS no
210461

Study contact information
Name:
 Mahitha Gummadi
Email: M.Gummadi@rbht.nhs.uk

Principal investigator
Dr Stephen John Wort

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Idiopathic and heritable pulmonary arterial hypertension

Study
National cohort study of Idiopathic and Heritable Pulmonary Arterial Hypertension

IRAS no
123349

Study contact information
Name:
 Rosa DaCosta
Email: R.DaCosta@rbht.nhs.uk

Principal investigator
Dr Stephen John Wort

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2 doses of CXA-10, vs placebo, in Pulmonary Arterial Hypertension

Study
Phase 2 multicenter, double-blind, placebo-controlled, efficacy, safety and pharmacokinetic study of 2 doses of CXA-10 on stable background therapy in subjects with Pulmonary Arterial Hypertension (PAH)

IRAS no
244109

Study contact information
Name: Rosa Da Costa
Email: R.DeCosta@rbht.nhs.uk

Principal investigator
Dr John Wort

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TRITON- Macitentan, Tadalafil and Selexipag Study in Patients with PAH

Study
The efficacy and safety of initial triple versus initial dual oral combination therapy in patients with newly diagnosed pulmonary arterial hypertension: A Multi-Centre, double-blind, placebo-controlled, Phase 3b Study

IRAS no
236384

Study contact information
Name: Dr John Wort
Email: S.Wort@rbht.nhs.uk

Principal investigator
Dr John Wort

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Quantitative MRI measures in PH (Version 1)

Study
Novel Quantitative Magnetic Resonance Imaging (MRI) Measures in the Assessment and Follow-up of patients with Pulmonary Hypertension (PH)

IRAS no
246688

Study contact information
Name: Mr Simon Padley
Email: S.Padley@rbht.nhs.uk

Principal investigator
Mr Simon Padley

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Utility of Emphasis-10 in Risk Stratification in Pulmonary Arterial Hypertension

Study
Utility of Emphasis-10 in Risk Stratification in Pulmonary Arterial Hypertension.

IRAS no
254446

Study contact information
Name: Dr John Wort
Email: S.Wort@rbht.nhs.uk

Principal investigator
Dr John Wort


Use of pulmonary arterial hypertension therapies in Fontan patients: Current practice across the UK

Study
Use of pulmonary arterial hypertension therapies in Fontan patients.

IRAS no
263589

Study contact information
Name: Dr Kostas Dimopoulos
Email: K.Dimopoulos@rbht.nhs.uk

Principal investigator
Dr Kostas Dimopoulos

Arterial stiffness

Study
Is arterial stiffness a consequence of respiratory failure?

IRAS no
210214

Study contact information
Name:
 Professor Michael Polkey
Email: m.polkey@rbht.nhs.uk

Principal investigator
Professor Michael Polkey

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Reducer-I

Study
Reducer-I: An observational study of the Neovasc Reducer System

IRAS no
190140

Study contact information
Name:
 Debra Dempster
Email: D.Dempster@rbht.nhs.uk

Principal investigator
Dr Ranil De Silva

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PPCI

Study
Lived experiences of heart attack and primary angioplasty (PPCI)

IRAS no
224728

Study contact information
Name:
 Marina Nicholas
Email: m.nicholas@rbht.nhs.uk

Principal investigator
Ms Marina Nicholas

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EBT in sarcoidosis

Study
Measure of exhaled breath temperature (EBT) in patients with sarcoidosis. 

IRAS no
215820

Study contact information
Name: Professor Athol Wells
Email: RBHILD@rbht.nhs.uk

Principal investigator
Professor Athol Wells

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The POSA Trial

Study
Positional Therapy for Obstructive Sleep Apnoea: a Randomised Controlled Trial to assess the effect on Health and Wellbeing in Older and Younger People.

IRAS no
252494

Study contact information
Name:
 Julia Kelly
Email: J.Kelly@rbht.nhs.uk

Principal investigator
Julia Kelly

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UK Mini Mitral

Study
Minimally invasive thoracoscopically-guided right minithoracotomy versus conventional sternotomy for mitral valve repair: a multicentre randomised controlled trial (UK Mini Mitral)

IRAS no
204506

Study contact information
Name:
 Claire Prendergast
Email: c.prendergast2@rbht.nhs.uk

Principal investigator
Mr Toufan Bahrami

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Sorin Universal Registry - Aortic Valve Replacement

Study
Sorin Universal Registry - Aortic Valve Replacement

IRAS no
152866

Study contact information
Name:
 Teijo Palovaara 
Email: t.palovaara@rbht.nhs.uk

Principal investigator
Mr George Asimakopoulos

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Blood flow patterns from 4D-flow MRI

Study
Can blood flow patterns from 4D-flow MRI be used to predict aortic wall degradation?

IRAS no
231355

Study contact information
Name:
 Yousuf Salmasi
Email: M.Salmasi@rbht.nhs.uk

Principal investigator
Professor John Pepper

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Prevention HARP 2

Study
Prevention of post-operative complications by using HMG-CoA reductase inhibitor in patients undergoing oesophagectomy. A multicentre, randomised, double blind, placebo controlled trial (Prevention HARP 2)

IRAS no
180853

Study contact information
Name:
 Paulo De Sousa
Email: P.DeSousa@rbht.nhs.uk

Principal investigator
Mr Eric Lim

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TOPIC 2: Thoracic Epidural and Paravertebral Blocks in reducing CPTP

Study
A randomised controlled trial to investigate the effectiveness of Thoracic Epidural and Paravertebral Blockade in reducing Chronic Post-Thoracotomy Pain: 2

IRAS no
248427

Study contact information
Name: Dr Nandor Marczin
Email: N.Marczin@rbht.nhs.uk

Principal investigator
Dr Nandor Marczin

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TISORB

Study
Prospective, Open, Multi-centre, Single-arm Study to Demonstrate the Feasibility of the CytoSorb 300 mL device to remove Ticagrelor during cardiopulmonary bypass in patients on ticagrelor undergoing emergent cardiothoracic surgery

IRAS no
264064

Study contact information
Name: Joanne Benton
Email: J.Benton@rbht.nhs.uk

Principal investigator
Dr Nandor Marczin

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Peak cough flow and respiratory function testing (spirometry)

Study
A cross sectional feasibility study examining the relationship between peak cough flow and respiratory function testing (spirometry) post bilateral sequential single lung transplantation, at a single centre cardiothoracic transplantation unit

IRAS no
218051

Study contact information
Name:
 Abigail Roberts
Email: A.Roberts@rbht.nhs.uk

Principal investigator
Dr Anna Reed

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Lung Transplant Risk Communication Tool

Study
The design of a personalised risk communication tool to aid patients’ understanding of the potential risks and benefits of listing for lung transplantation.

IRAS no
245851

Study contact information
Name:
 Dr Martin Carby
Email: M.Carby@rbht.nhs.uk

Principal investigator
Dr Martin Carby

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LACTATE in OHT

Study
Significance of hyperlactataemia during heart transplantation.

IRAS no
259590

Study contact information
Name:
 Ms Ana Doce Hurtado
Email: A.HurtadoDoce@rbht.nhs.uk

Principal investigator
Ms Ana Doce Hurtado


PC945 in Aspergillosis in Lung transplant recipients

Study
An open-label, pilot study to assess safety, tolerability, pharmacokinetics and effects of inhaled PC945 in the pre-emptive treatment of Aspergillus fumigatus colonisation in lung transplant recipients

IRAS no
256412

Study contact information
Name:
 Paula Rogers
Email: P.Rogers@rbht.nhs.uk

Principal investigator
Dr Anna Reed

Molecular and cellular pathogenesis of bone marrow failure syndromes

Study
Investigation of the molecular and cellular pathogenesis of bone marrow failure syndromes

IRAS no
97361

Study contact information
Name:
 Mr Andreas Hoschtitzky
Email: A.Hoschtitzky@rbht.nhs.uk

Principal investigator
Mr Andreas Hoschtitzky


Multisystem and autonomic complications of NMD on NIV

Study
Growing up on non-invasive ventilation: assessment of multisystem and autonomic complications of neuromuscular and neurological disorders in young adults.

IRAS no
266270 

Study contact information
Name:
 Lydia Spurr
Email: l.spurr@rbht.nhs.uk

Principal investigator
Professor Anita Simonds


Mindfulness in chest pain (MIPIC)

Study
Mindfulness based intervention in patients with persistent pain in chest (MIPIC) of non-cardiac cause - a feasibility randomised control study.

IRAS no
253106

Study contact information
Name:
 Michelle Rackham
Email: M.Rackham@rbht.nhs.uk

Principal investigator
Dr Tarun Mittal


The TARGET BP OFF-MED Trial

Study
A Phase 2, multicenter, blinded, sham procedure-Controlled Trial of Renal Denervation by the Peregrine System Kit, in Subjects with Hypertension, in the Absence of Anti-hypertensive Medications

IRAS no
250980

Study contact information
Name: Debra Dempster
Email: D.Dempster@rbht.nhs.uk

Principal investigator
Dr Ranil De Silva

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