Respiratory medicine (lung)
Laboratory medicine
Spoken Languages


Areas of expertise

  • Occupational respiratory diseases, particularly lung cancer, mesothelioma, COPD and asthma
  • Occupational risk assessment at workplace
  • Epidemiological methods in occupational health research

Research interests

  • To study occupational, environmental and genetic risk factors and their interactions in respiratory disease aetiology, with particular focus on asthma, COPD and lung cancer.
  • To evaluate gender differences in respiratory disease susceptibility, particularly in relation to tobacco smoking and occupational hazards exposure
  • To develop new standard methods to assess occupational exposure and detect work-related diseases in epidemiological studies

Current research projects

Dr De Matteis is currently working on the UK Biobank study, a population-based cohort of more than half a million subjects, aged 40-69, enrolled throughout the UK. The aim of the study is to:

  • estimate the burden of COPD attributable to occupational exposure in the UK Biobank population, taking into account potential confounders such as tobacco smoking
  • develop a new and efficient web-based tool to collect and code lifetime occupational exposure in large population-based epidemiological studies.


Dr De Matteis graduated from the School of Medicine of the University of Milan (Italy) in 2005, where she also completed her specialty in occupational medicine in 2010 and achieved a PhD in occupational medicine in 2013.

She currently holds the position of academic clinical lecturer at the department of respiratory epidemiology, occupational medicine and public health, National Heart and Lung Institute (NHLI), Imperial College London.

She also practices in the Occupational Lung Disease clinic at the Royal Brompton Hospital.


Dr De Matteis carries out extensive graduate and postgraduate teaching on occupational health and epidemiological methods both inside and outside the Trust.

Twice a year, she also leads and lectures on the successful, two-day 'Introductory Medical Statistics,' course which focuses on core stats.  


Dr De Matteis is an independent scientific member of the Industrial Injuries Advisory Council for the Department for Work and Pensions in the UK.

She is also a member of the European Respiratory Society's (ERS) Environment and Health Committee, Brussels, Belgium; as well as a member of the UK Group of Occupational Respiratory Disease Specialists. 


She is often called on to act as a referee for international peer-reviewed scientific journals. A selection of recent publications include:

  • De Matteis S, et al. Current and new challenges in occupational lung diseases. Eur Respir Rev. 2017 Nov 15;26(146
  • De Matteis S, et al. Occupational self-coding and automatic recording (OSCAR): a novel web-based tool to collect and code lifetime job histories in large population-based studies. Scand J Work Environ Health. 2017 Mar 1;43(2):181-186
  • De Matteis S, et al. Occupations associated with COPD risk in the large population-based UK Biobank cohort study. Occup Environ Med. 2016 Jun;73(6):378-84
  • De Matteis S, Cullinan P. Occupational asthma in cleaners: a challenging black box. Occup Environ Med. 2015 Nov;72(11):755-6