This section describes the clinical evidence for benefit from coronary collateral channels. There is data to suggest the presence of a protective effect in patients sustaining myocardial infarction regardless of whether they receive reperfusion therapy, and whether the collaterals were preformed. The role of pre-infarction angina in stimulating collateral development remains a contentious issue.
Smith RD, Ilsley CD. Clinical contribution of the collateral circulation to myocardial protection. Coronary Art Dis 2004; 15: 393-398