Computed tomography (CT) is routinely used for diagnosis and characterisation of idiopathic pulmonary fibrosis (IPF). The technique however has limited sensitivity in detection and monitoring of early fibrotic changes. The aim of this study was to evaluate T1 characteristics in the radiologically diseased lung parenchyma in IPF patient compared to apparently normal parenchyma in both interstitial lung disease (ILD) patients and healthy volunteers and to investigate the feasibility of the technique in prediction of early fibrotic lung changes that may not be visible on CT.
Publication information
8. Saeed Mirsadraee, Matthew Tse, Lucy Kershaw, Scott Semple, Nicola Schembri, Calvin Chin, John T. Murchison, Nik Hirani, Edwin J. R. van Beek. T1 characteristics of interstitial pulmonary fibrosis on 3T MRI – a predictor of early interstitial change? Quant Imaging Med Surg. 2016 Feb;6(1):42-9.