Cardiology (heart)
Spoken Languages


After qualifying from King’s College school of medicine and dentistry in 1995, Dr de Silva completed training in general medicine, general cardiology and interventional cardiology at Royal Brompton, Chelsea and Westminster, Northwick Park, Hammersmith, and St. Mary’s hospitals.

Dr de Silva undertook his PhD research while a medical student under the supervision of Professor Attilio Maseri and Professor Giovanni Mann at the MRC Cyclotron Unit at Hammersmith Hospital and the Research Institute for Brain and Blood Vessels in Akita, Japan. His research focused on assessment of the pathophysiology of myocardial ischaemia and reperfusion using cardiac positron emission tomography.

He then undertook post-doctoral research at the National Heart Lung and Blood Institute at the National Institutes of Health (NIH) in the USA. His work focused on X-ray fused with magnetic resonance imaging (MRI) and real-time MRI-guided endovascular intervention, with particular emphasis on targeted delivery of cardiac cell therapies.

Areas of expertise

Dr Ranil de Silva is a consultant interventional cardiologist. His main areas of interest include:

  • complex coronary artery disease
  • coronary angioplasty
  • intracoronary imaging
  • acute coronary syndromes
  • cardiac imaging
  • refractory hypertension
  • biologics for cardiovascular disease

He is also associate theme leader in complex coronary disease research in the cardiovascular research unit at Royal Brompton Hospital. 


Dr de Silva’s main research interests include: 

  • new therapies for patients with refractory angina – coronary sinus reducer
  • novel intracoronary imaging derived biomarkers to stratify risk of progression of coronary atherosclerotic lesions
  • acute coronary syndromes / stable coronary artery disease – treatment, biomarkers, risk stratification
  • cardiac MRI – diffusion tensor imaging of myocardial infarction
  • refractory hypertension

He has been the recipient of an NIH Bench to Bedside Award and has ongoing collaborative research programmes with investigators at the  National Institutes of Health and the University of Wisconsin in the USA.

Lectures and teaching

Dr de Silva regularly lectures on pathophysiology and management of acute coronary syndromes, refractory angina, and image-guided endovascular intervention at local, national and international meetings.

At the Trust, Dr de Silva regularly performs postgraduate teaching in cardiology to visiting physicians and students from Europe and Japan.

He is on the organising committee of the Grand Round lecture series at Royal Brompton & Harefield NHS Foundation Trust. He is also responsible for the organisation of Imperial College London's annual angina study day.


  • Foulkes Foundation Fellowship (1992 to 1995)
  • Winner, Young Investigator Competition, Japanese College of Cardiology, (1992)
  • Winning team, Medical Futures Cardiovascular Innovation Award (2008)

Private patient referral 

If you would like to make an appointment with this specialist for private care, contact the RB&HH Specialist care team

Research Publications

Hypertension is a key determinant of cardiovascular disease morbidity and mortality, directly accounting for approximately 10% of deaths in India.

The benefit of beta-blockers in the management of patients with heart failure and left ventricular dysfunction has been incontrovertibly established in multiple contemporary randomized clinical tri