Respiratory medicine (lung)
Spoken Languages


Dr Alexandra Nanzer-Kelly undertook her specialist respiratory training in London, working across general and specialist respiratory and general medicine at St Mary’s and Chelsea and Westminster Hospitals, completing her specialist training here at Royal Brompton & Harefield NHS Foundation Trust.

Alongside her clinical training, she undertook research with the Medical Research Council (MRC) and Asthma UK’s Centre in Allergic Mechanisms of Asthma at King’s College London, in collaboration with the Blizard Institute at Barts and the London School of Medicine and Dentistry and supported by Asthma UK.

Her work focused on the immune regulation of severe, therapy-refractory asthma and her thesis was presented for her PhD from the University of London. Her studies have contributed to our understanding of the immunology of severe asthma and she has published widely on this subject and also contributed to textbooks in these areas of clinical and scientific interest.

Dr Nanzer-Kelly has also received an award from the Edward Jenner programme by the NHS Leadership Academy.

Clinical expertise

Dr Nanzer-Kelly is a consultant respiratory physician at Royal Brompton Hospital and is trained in all areas of respiratory medicine. She specialises in the diagnosis and management of severe asthma and the complications of its treatment.

Her work provides patients with severe asthma a safe, efficient and patient centered service and is developing a novel clinical service in collaboration with the Trust’s metabolic specialists.

Through her specialist metabolic asthma clinic, with a team of physiotherapists and dieticians, patients referred and managed at the Royal Brompton are offered a unique, integrated, whole-system programme of treatment. 

This programme focuses on: 

  • physical activity
  • diet
  • metabolism
  • bone health
  • psychological health.

There is also world-leading attention to the airways and breathing.

Research interests

Dr Nanzer-Kelly has particular specialist interests in the adverse metabolic, skeletal and psychological effects of steroid therapy that many patients with severe asthma are dependent on and the management of asthma in the overweight patient.

She has unique training in this area, having spent part of her postgraduate training at the Department of Endocrinology at St Bartholomew’s Hospital, where she saw the deleterious effects of endogenous Cushing’s syndrome while studying the role of ghrelin on pituitary tumour development.

She has maintained and developed this interest in steroid therapy through her clinical training and her research into the immunology of steroid insensitive asthma.


Dr Nanzer-Kelly lectures on the Imperial College London allergy MSc course. She is a clinical and educational supervisor to trainees at the Royal Brompton and has examined for Barts and the London School of Medicine objective structured clinical examination (OSCE) examinations.

Research Publications

An 18-year-old patient with metabolic myopathy due to long-chain fatty acid coenzyme A dehydrogenase-deficiency1 ,

Asthma is a chronic inflammatory disease that has reached epidemic proportions worldwide. It is treatable in the majority of patients, but there is no cure.