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The Clinical COPD Questionnaire (CCQ): Cut-point for GOLD 2013 classification
… a higher level of symptoms using the following cut points: mMRC ≥ 2 or a CAT score ≥ 10, with a preference for … MI, Man WD. The Clinical COPD Questionnaire (CCQ): Cut-point for GOLD 2013 classification.  Am J Respir Crit Care … a higher level of symptoms using the following cut points: mMRC ≥ 2 or a CAT score ≥ 10, with a preference for …
Research article
Cardiac resynchronisation therapy for critically ill patients with left ventricular systolic dysfunction
… median left ventricular ejection fraction (LVEF) was 26% (IQR 13) and median QRS duration 146 ms (IQR 29). Eleven … on mechanical ventilation. Post CRT LVEF improved from 26% to 39% (p=0.027) and the estimated glomerular filtration … a median follow up of 392 days (IQR 538), 7 (33%) patients died. In-hospital and one year mortality rates were 8.3% and …
Research article
Atrial fibrillation in advanced heart failure
… 0.19 +/- 0.07. Seventy-five patients (19%) had paroxysmal (26 patients) or chronic (49 patients) atrial fibrillation. … After a mean follow-up of 236 +/- 303 days, 98 patients died: 56 (57%) died suddenly, and 36 (37%) died of progressive heart … 0.19 +/- 0.07. Seventy-five patients (19%) had paroxysmal (26 patients) or chronic (49 patients) atrial fibrillation. …
Research article
Quadriceps wasting and physical inactivity in patients with COPD
… Connolly BA, Puthucheary ZA, Walsh SLF, Bloch SA, Sidhu PS, Hart N, Kemp PR, Moxham J, Polkey MI, Hopkinson NS. … Connolly BA, Puthucheary ZA, Walsh SLF, Bloch SA, Sidhu PS, Hart N, Kemp PR, Moxham J, Polkey MI, Hopkinson NS. …
Research article
Optimization of T1 Mapping at 3T in Patients with Aortic Stenosis
… were assessed. After establishing the optimal time point and myocardial region for analysis, we compared the … with AS compared with controls (ECV 28.3 ± 1.7 vs. 26.0 ± 1.6%, P < 0.001; λ 0.46 ± 0.03 vs. 0.44 ± 0.03, P = … were assessed. After establishing the optimal time point and myocardial region for analysis, we compared the …
Research article
Utility of a novel rapid high-resolution mapping system in the catheter ablation of arrhythmias - An initial human experience of mapping the atria and the left ventricle.
… maps based on automatic annotation of thousands of points was recently released for clinical use. This is the … in 11 (4 to 15) min, consisting of 7,220 (3,467 to 10,947) points, 22 left atrial maps in 11 (6 to 19) min, consisting of 7,818 (4,379 to 12,262) points and 10 left ventricular maps in 37 (14 to 43) min, …
Research article
On behalf of the Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) study investigators Six Minute Walk Test in COPD: Minimal Clinically Important Difference for Death or Hospitalization
… MAIN RESULTS: Of subjects with change in the 6MWD data, 94 died, and 323 were hospitalized. 6MWD fell by 29.7 m (SD, 82.9 m) more among those who died than among survivors (P < 0.001). A reduction in … MAIN RESULTS: Of subjects with change in the 6MWD data, 94 died, and 323 were hospitalized. 6MWD fell by 29.7 m (SD, …
Research article
Steps to better understand severe asthma
… despite correct treatment. In the UK, three people die every day from asthma.  Publication information Nanzer AM … despite correct treatment. In the UK, three people die every day from asthma.  Publication information Nanzer AM …
Research article
Interventional cardiovascular procedures guided by real-time MR imaging: An interactive interface using multiple slices, adaptive projection modes and live 3D renderings
… modes and live 3D renderings.J Magn Reson Imaging 2007;26:1429-1435 … modes and live 3D renderings.J Magn Reson Imaging 2007;26:1429-1435 …
Research article
Life-years gained from defibrillator implantation: markedly nonlinear increase during 3 years of follow-up and its implications
… the cumulative benefit in life-years gained at time points from 3 months to 3 years. Because the trial … we expressed for each study the benefit at each time point as the proportion of benefit at 3 years. The average … yet benefit grows with time, the choice of an early time point artificially reduces apparent benefit and artificially …
Research article