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The Clinical COPD Questionnaire (CCQ): Cut-point for GOLD 2013 classification
… a higher level of symptoms using the following cut points: mMRC ≥ 2 or a CAT score ≥ 10, with a preference for … MI, Man WD. The Clinical COPD Questionnaire (CCQ): Cut-point for GOLD 2013 classification.  Am J Respir Crit Care … a higher level of symptoms using the following cut points: mMRC ≥ 2 or a CAT score ≥ 10, with a preference for …
Research article
Not all wheeze is asthma: time for patients to exercise their rights
… is at best imprecise and at worst no better than a coin toss.5–7 In other words, in young individuals objective … is at best imprecise and at worst no better than a coin toss.5–7 In other words, in young individuals objective …
Research article
Quadriceps wasting and physical inactivity in patients with COPD
… Connolly BA, Puthucheary ZA, Walsh SLF, Bloch SA, Sidhu PS, Hart N, Kemp PR, Moxham J, Polkey MI, Hopkinson NS. … Connolly BA, Puthucheary ZA, Walsh SLF, Bloch SA, Sidhu PS, Hart N, Kemp PR, Moxham J, Polkey MI, Hopkinson NS. …
Research article
Atrial fibrillation in advanced heart failure
… 0.19 +/- 0.07. Seventy-five patients (19%) had paroxysmal (26 patients) or chronic (49 patients) atrial fibrillation. … After a mean follow-up of 236 +/- 303 days, 98 patients died: 56 (57%) died suddenly, and 36 (37%) died of progressive heart … 0.19 +/- 0.07. Seventy-five patients (19%) had paroxysmal (26 patients) or chronic (49 patients) atrial fibrillation. …
Research article
Utility of a novel rapid high-resolution mapping system in the catheter ablation of arrhythmias - An initial human experience of mapping the atria and the left ventricle.
… maps based on automatic annotation of thousands of points was recently released for clinical use. This is the … in 11 (4 to 15) min, consisting of 7,220 (3,467 to 10,947) points, 22 left atrial maps in 11 (6 to 19) min, consisting of 7,818 (4,379 to 12,262) points and 10 left ventricular maps in 37 (14 to 43) min, …
Research article
On behalf of the Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) study investigators Six Minute Walk Test in COPD: Minimal Clinically Important Difference for Death or Hospitalization
… MAIN RESULTS: Of subjects with change in the 6MWD data, 94 died, and 323 were hospitalized. 6MWD fell by 29.7 m (SD, 82.9 m) more among those who died than among survivors (P < 0.001). A reduction in … MAIN RESULTS: Of subjects with change in the 6MWD data, 94 died, and 323 were hospitalized. 6MWD fell by 29.7 m (SD, …
Research article
Steps to better understand severe asthma
… despite correct treatment. In the UK, three people die every day from asthma.  Publication information Nanzer AM … despite correct treatment. In the UK, three people die every day from asthma.  Publication information Nanzer AM …
Research article
Life-years gained from defibrillator implantation: markedly nonlinear increase during 3 years of follow-up and its implications
… the cumulative benefit in life-years gained at time points from 3 months to 3 years. Because the trial … we expressed for each study the benefit at each time point as the proportion of benefit at 3 years. The average … yet benefit grows with time, the choice of an early time point artificially reduces apparent benefit and artificially …
Research article
The impact of age on clinical outcomes following cardiac resynchronisation therapy
… (n = 46, mean ± SD 80.7 ± 4.1 years). The primary end point was a composite of all-cause mortality or HF … of 28.5 ± 33.7 months, the event rate for the primary end point was significantly higher in the elderly compared to … and ICD status, the difference in the composite end point rates was attenuated and no longer significant (HR …
Research article
Intra-cavity right ventricular metastasis
… but remained haemodynamically compromised and died shortly after admission. Post-mortem examination showed … but remained haemodynamically compromised and died shortly after admission. Post-mortem examination showed …
Research article