Background and qualifications
Dr Andrew Scott graduated from Manchester University in 2004 with a first class degree (MPhys) in physics. In 2006 he was awarded an MSc in medical engineering and physics. During this MSc, he also completed the Institute of Physics and Engineering in Medicine part one training in medical physics, with specialisation in MRI, nuclear medicine and radiotherapy at hospitals across London. In 2009, Imperial College London awarded Dr Scott a PhD in cardiac MRI physics.
His PhD was carried out at Royal Brompton Hospital, addressing respiratory motion in coronary vessel wall imaging. This was followed by a post-doctoral position as a research MRI physicist at St Bartholomew’s and The Royal London Hospitals, developing novel techniques for imaging the upper vocal tract during speech, in young patients with cleft palates. In October 2012 he took up his current position as senior physicist in the cardiovascular biomedical research unit based at Royal Brompton Hospital, developing techniques in cardiac diffusion tensor imaging.
Dr Scott’s current research involves developing techniques for diffusion tensor imaging (DTI) of the heart, which provides insights into the microstructure of the heart, including the orientation of the heart muscle cells. Within the DTI team his role involves developing computer programs (pulse sequences) which control data collection from the MRI scanner and considering new ways to improve this process. He is interested in possible ways to obtain more detailed, higher resolution maps of cardiac microstructure and how these techniques can translate into clinically reliable tools which benefit patients.
Further information and research publications
In addition to the peer-reviewed publications listed below, Dr Scott was presented with a junior fellowship at the International Society for Magnetic Resonance in Medicine annual meeting in 2012. In 2014, he was nominated for an Early Career Award at the Society for Cardiovascular Magnetic Resonance annual meeting.
Wylezinkska M, Pinkstone M, Hay M, Scott AD, Birch MJ, Miquel ME, Impact of orthodontic appliances on the quality of craniofacial anatomical magnetic resonance imaging and real-time speech imaging. The European Journal of Orthodontics 2015.
Ferreira PF, Kilner PJ, McGill LA, Nielles-Vallespin S, Scott AD et al. In vivo cardiovascular magnetic resonance diffusion tensor imaging shows evidence of abnormal myocardial laminar orientations and mobility in hypertrophic cardiomyopathy. Journal of Cardiovascular Magnetic Resonance 16:87. 2014. * - Winner of the Gerald Pohost Best Manuscript in JCMR Award 2015.
Scott AD, Wylezinska M, Birch MJ, Miquel ME. Speech MRI: Morphology and function. Physica Medica 30(604) 2014.
Scott AD, Ferreira PF, Nielles-Vallespin S, Gatehouse PD, McGill LA, Kilner P, Pennell DJ, Firmin DN. Optimal diffusion weighting for in vivo cardiac diffusion tensor imaging. Magnetic Resonance in Medicine 2014.
Elizabeth M Tunnicliffe, Andrew D Scott, Pedro Ferreira, Rina Ariga, Laura-Ann McGill, Sonia Nielles-Vallespin, Stefan Neubauer,Dudley J Pennell, Matthew D Robson, David N Firmin. Intercentre reproducibility of cardiac apparent diffusion coefficient and fractional anisotropy in healthy volunteers. Journal of Cardiovascular Magnetic Resonance 16:31. 2014.
McGill LA. Ismail TF, Nielles-Vallespin S, Ferreira P, Scott AD, et al. Reproducibility of in-vivo diffusion tensor cardiovascular magnetic resonance in hypertrophic cardiomyopathy. Journal of Cardiovascular Magnetic Resonance 15:22. 2012.
AD Scott, R Boubertakh, MJ Birch, ME Miquel. Adaptive averaging applied to dynamic imaging of the soft palate. Magnetic Resonance in Medicine 70:3. 2012.
AD Scott, R Boubertakh, MJ Birch, ME Miquel. Towards clinical assessment of velopharyngeal closure using MRI: evaluation of real-time MRI sequences at 1.5 and 3 T. British Journal of Radiology 85(1019). 2012.
ME Miquel, AD Scott, ND Macdougall, R Boubertakh, N Bharwani, AG Rockall. In vitro and in vivo repeatability of abdominal diffusion-weighted MRI. British Journal of Radiology 85(1019). 2012
AD Scott, J Keegan, DN Firmin. Beat-to-beat respiratory motion correction with near 100% efficiency: a quantitative assessment using high-resolution coronary artery imaging. Magnetic resonance imaging 29(4). 2011
AD Scott, J Keegan, DN Firmin. High-resolution 3D coronary vessel wall imaging with near 100% respiratory efficiency using epicardial fat tracking: Reproducibility and comparison with standard methods. Journal of Magnetic Resonance Imaging 33(1). 2011
AD Scott, J Keegan, RH Mohiaddin, DN Firmin. Noninvasive detection of coronary artery wall thickening with age in healthy subjects using high resolution MRI with beat-to-beat respiratory motion correction. Journal of Magnetic Resonance Imaging 34(4). 2011.
AD Scott, J Keegan, DN Firmin. Motion in Cardiovascular MR Imaging. Radiology 250 (2). 2009.