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Royal Brompton & Harefield NHS Foundation Trust
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Bronchiectasis treatments

Our research

Active research studies

The Trust hosts a variety of research studies covering the breadth of its clinical practice. These are funded by a variety of sponsors including National Institute for Health Research (NIHR), UK research councils, European funding agencies, research charities and industry. 

Below is a list of approved projects that are currently recruiting volunteers.


Research studies

Specialty CategoryResearch titleStudy contact informationMore info
Interstitial lung disease & pulmonary fibrosisA randomised, double-blind, multi centre, placebo-controlled dose escalation study in healthy subjects investigating the safety, tolerability and pharmacokinetic properties of TD139, a galectin-3 inhibitor, followed by an expansion cohort treating subjectSindhu SivagnanasithiyarMore info
Interstitial lung disease & pulmonary fibrosisA double blind, randomized, placebo-controlled trial evaluating efficacy and safety of oral nintedanib, 150 mg twice daily for 52 weeks (with follow up until last patient out up to a maximum of 2 years) in patients with ?Systemic Sclerosis associated inteSindhu SivagnanasithiyarMore info
Interstitial lung disease & pulmonary fibrosisEMBARC: European Bronchiectasis RegistryNajwas SoussiMore info
PaediatricsEDITS - Early Development in Tuberous Sclerosis - Designing a protocol to measure the developmental trajectory of infants with tuberous sclerosis complex.Charlotte TyeMore info
PaediatricsPreschool wheeze: Inflammation/Infection Guided Management (PrIGMa)Yvonne BinghamMore info
PaediatricsTORPEDO-CFLaura HayersMore info
Pulmonary hypertensionTRANSFORM-UK: A Therapeutic Open Label Study of Tocilizumab in the Treatment of Pulmonary Arterial HypertensionRosa Da CostaMore info
Pulmonary hypertensionNational Cohort Study of Pulmonary Arterial HypertensionNatalie Dormand, Abigail Chikwanha or Emily ShawMore info
Structural heart diseaseSorin Universal REgistry on Aortic Valve ReplacementSelvaraj ShanmuganathanMore info
Structural Heart DiseaseHemodynamic patterns in different aortic valve and root prosthesisOmar JarralMore info

See details of the Trust’s performance for all clinical trials reported to the NIHR (PDF, 283KB), for the set-up and delivery of studies in the period 1 January 2017 to 31 December 2017.

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