Background and training
Dr Omar Usmani qualified in medicine at King's College London. He trained in respiratory and general internal medicine at St Thomas', King's College and Bromley hospitals. He did his PhD at Imperial College, London, with his research work published in BBC News' Online Stories on asthma treatments and coughs.
In 2005, he received the Best PhD Thesis Prize at the National Heart and Lung Institute (NHLI), Imperial College London. He also received an Alavi-Mandell Award from the American Society of Nuclear Medicine. These awards were related to inhaled aerosol science and drug delivery to lungs.
Areas of expertise
Dr Usmani is an honorary consultant physician at the Trust and a clinical senior lecturer at the NHLI.
He runs the chronic cough clinic at Royal Brompton Hospital. He is part of the consultant-led chronic obstructive pulmonary disease (COPD) service. He also sees patients with asthma in the asthma lab.
Dr Usmani's research interests include:
- patients with asthma and COPD
- inhalers and inhaled drug delivery techniques
- lung imaging
- physiology of airways
- pharmacology of coughs
- molecular biology of inhaled drugs
Teaching and publications
Dr Usmani has presented his research at national and international conferences.
He is also on the editorial board for the online journal Cough.
Published research papers
¨Biddiscombe MF, Barnes PJ, Usmani OS. Generating monodisperse pharmacological aerosols using a spinning top aerosol generator. J Aerosol Med. 19:245-253, 2006.
¨Usmani OS, Biddiscombe MF, Barnes PJ. Regional lung deposition and bronchodilator response as a function of β2-agonist particle size. Am J Respir Crit Care Med. 172:1497-1504, 2005.
¨Usmani OS, Ito K, Maneechotesuwan K, Ito M, Johnson M, Barnes PJ, Adcock IM. Glucocorticoid receptor nuclear translocation in airway cells after inhaled therapy. Am J Respir Crit Care Med. 172:704-712, 2005.
¨Haque RA, Usmani OS, Barnes PJ. Chronic idiopathic cough: a discrete clinical entity? Chest. 127:1710-1713, 2005.
¨Usmani OS, Belvisi MG, Patel HJ, Crispino N, Birrell MA, Korbonits M, Korbonits D, Barnes PJ. Theobromine inhibits sensory nerve activation and cough. FASEB J. 19:231-233, 2005.
¨Niimi A, Nguyen LT, Usmani O, Mann B, Chung KF. Reduced pH and chloride levels in exhaled breath condensate of patients with chronic cough. Thorax. 59:608-612, 2004.
¨Usmani OS, Biddiscombe MF,Underwood SR, Barnes PJ. Characterization of the generation of radiolabeled monodisperse albuterol particles using the spinning top aerosol generator. J Nucl Med. 4: 69-73, 2004.
¨Usmani OS, Biddiscombe MF, Nightingale JA, Underwood SR, Barnes PJ.The effects of bronchodilator particle size in asthmatics using monodisperse aerosols. J Appl Physiol. 95: 2106–2112, 2003.
¨Usmani OS*, Biddiscombe MF*, Barnes PJ. A system for the production and delivery of monodisperse salbutamol aerosols to the lungs. Int J Pharm. 254:243-253, 2003. *joint first authors
¨Adcock IM, Maneechotesuwan K, Usmani OS. Molecular interactions between glucocorticoids and long-acting beta2-agonists. J Allergy Clin Immunol. 110:S261-268, 2002.
¨Tomita K, Lim S, Hanazawa T, Usmani O, Stirling R, Chung KF, Barnes PJ, Adcock IM. Attenuated production of intracellular IL-10 & -12 in monocytes from patients with severe asthma. Clin Immunol. 102:258-266, 2002.
¨Cannon J, Usmani OS, Chambers J, Thompson RP, Twort CH. Intrapulmonary shunting and hepatopulmonary syndrome. Hosp Med. 66:312-313, 2005.