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Dr Toby Maher

Dr Toby Maher

Consultant respiratory physician

Background and training


Dr Toby Maher qualified at Southampton Medical School and trained in respiratory medicine at Royal Brompton Hospital, the Transplant Unit at Harefield Hospital and at St Mary’s Hospital, Paddington. During his training he gained an MSc in respiratory medicine from Imperial College London.

 

In 2005 Dr Maher was awarded a Wellcome Trust Clinical Research Fellowship that enabled him to study the molecular mechanisms involved in the development of idiopathic pulmonary fibrosis. This research was undertaken at the Centre for Respiratory Research, University College London and culminated in the award of a PhD.

           

Dr Maher is consultant respiratory physician. He also holds the positions of honorary senior lecturer at the National Heart and Lung Institute, Imperial College London, and honorary senior research associate at University College London.  


Areas of expertise

    

Dr Maher has a subspecialty interest in interstitial lung disease and his areas of expertise include: 


  • idiopathic pulmonary fibrosis (IPF)
  • hypersensitivity pneumonitis
  • sarcoidosis
  • Langerhan's cell histiocytosis
  • Lymphangeiolyomyomatosis


He also manages pulmonary fibrosis and lung disease associated with systemic conditions such as Rheumatoid arthritis, Scleroderma and Wegener’s granulomatosis.


Research interests


Dr Maher's research interests include: 


  • basic and translational research into idiopathic pulmonary fibrosis
  • the use of acoustic lung imaging in diagnosis and disease monitoring in patients with chronic respiratory conditions
  • biomarker discoveries and development of new treatments for interstitial lung disease. 


Dr Maher is also the lead consultant for clinical trials in the Interstitial Lung Disease Unit.

 

He works closely with scientists at the Centre for Respiratory Research, University College London and has active collaborations with Nottingham University and McMaster University, Canada.

 

As well as publishing original research, expert reviews and book chapters, Dr Maher acts as an expert reviewer for a number of international respiratory journals and is an associate editor for Respirology.

 

This video has Dr Maher talking about IPF and highlighting the Trust’s research into the condition.


Teaching


Dr Toby Maher presented at the American Thoracic Society Meeting in San Francisco in May 2012 and the 17th International Colloquium on Lung and Airway Fibrosis in Modena, Italy in September 2012.



Memberships


Dr Maher is actively involved in a number of specialist societies, and holds the following positions:


 



Recent publications

 

  • Krupiczojc MA, Scotton CJ, Koenigshoff M, Lee YCG, Kaminski N, Morser J, Post JM, Maher TM, Nicholson AG, Moffatt JD, Laurent GJ, Eickelberg O, Chambers RC 'Local extrahepatic upregulation of coagulation factor X: potential novel role in fibrotic lung disease', J Clin Invest 2009; 119: 2550 – 2563. [Link].

 

  • Maher TM, Wells AU 'Lost in translation: from animal models of pulmonary fibrosis to human diseas', Respirology 2009; 14: 915 – 916. [Link].

 

  • Xu MY, Porte J, Knox AJ, Weinreb PH, Maher TM, Violette SM, McAnulty RJ, Sheppard D, Jenkins RG 'Lysophosphatidic acid induces avβ6 integrin-mediated TGF-β activation via the LPA2 receptor and the small G protein Gαq', Am J Path 2009: 174; 1264 -1279.[Link].

 

  

  • Maher TM'Understanding non-specific interstitial pneumonia: the need for a diagnostic gold standard', Am J Resp Crit Care Med 2009; 179: 255 – 256. [Link].

  

  • Maher TM, Wells AU 'Optimal therapy for idiopathic pulmonary fibrosis', Thorax 2008; 63: 1120 – 21. [Link].

  

  • Mordechai Y, Gat M, Myer JJ, Freidman PJ, Maher TM, Madison JM 'Vibration response imaging technology in healthy subjects', AJR Am JRoentgenol 2008: 191; 845 - 852[Link].

  

  • Maher TM'Diagnosis of idiopathic pulmonary fibrosis and its complications', Expert Opin Med Diagn 2008; 2: 1317 – 1331. [Link].

  

  • Maher TM, Gat M, Allen DJ, Devaraj A, Wells AU, Geddes DM 'The reproducibility of dynamically represented acoustic lung images from healthy individuals', Thorax 2008; 63: 542 – 548 [Link].

 

  • Maher TM 'Diffuse parenchymal lung disease', Medicine 2008; 36: 265 - 272. [Link].

  

  • Goh NS, Desai SR, Veeraraghavan S, Hansell DM, Copley SJ, Maher TM, Corte TJ, Sander CR, Ratoff J, Devaraj A, Bozovic G, Denton CP, Black CM, du Bois RM, Wells AU 'Interstitial lung disease in systemic sclerosis: a simple staging system', Am J Respir Crit Care Med 2008; 177: 1178 – 1179. [Link].

 

  • Maher TM, Wells AU, Laurent GJ 'Idiopathic pulmonary fibrosis: Multiple causes multiple mechanisms?', Eur Repir J 2007; 30: 835 – 839. [Link].

 

  • Thornton C, Maher TM, Hansell D, Nicholson AG, Wells AU 'Pulmonary fibrosis associated with psychotropic drug therapy: a case report', Journal of Medical Case Reports 2009, 3:126 [Link].

 

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